Date published: 2026-4-4

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1-Chlorobutane (CAS 109-69-3)

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Alternate Names:
Butyl chloride
Application:
1-Chlorobutane is a chromatography solvent
CAS Number:
109-69-3
Molecular Weight:
92.57
Molecular Formula:
C4H9Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Chlorobutane is a chemical compound that functions as an alkylating agent in organic synthesis. It acts as an alkylating agent by donating an alkyl group to nucleophiles, leading to the formation of new carbon-carbon bonds. 1-Chlorobutane′s mechanism of action involves the substitution of the chlorine atom with the nucleophile, resulting in the formation of a new carbon-carbon bond. This process functions as the synthesis of various organic compounds agrochemicals, and other fine chemicals. I1-Chlorobutane plays a role in the creation of complex organic molecules by facilitating alkyl group transfer reactions. Its ability to undergo nucleophilic substitution reactions may be a useful for chemists working on the synthesis of diverse organic compounds.


1-Chlorobutane (CAS 109-69-3) References

  1. Analysis of vinylidene chloride and 1-chlorobutane in foods packaged with polyvinylidene chloride casing films by headspace gas chromatography/mass spectrometry (GC/MS).  |  Ohno, H. and Kawamura, Y. 2006. Food Addit Contam. 23: 839-44. PMID: 16807210
  2. Dehalogenation of gaseous 1-chlorobutane by dehydrated whole cells: Influence of the microenvironment of the halidohydrolase on the stability of the biocatalyst.  |  Marchand, P., et al. 2009. Biotechnol Bioeng. 103: 687-95. PMID: 19301412
  3. Questioning the photophysical model for the indole chromophore in the light of evidence obtained by controlling the non-specific effect of the medium with 1-chlorobutane as solvent.  |  Catalán, J. and Catalán, JP. 2011. Phys Chem Chem Phys. 13: 15022-30. PMID: 21761037
  4. Computational evidence for the degradation mechanism of haloalkane dehalogenase LinB and mutants of Leu248 to 1-chlorobutane.  |  Wang, J., et al. 2018. Phys Chem Chem Phys. 20: 20540-20547. PMID: 30051124
  5. Rate Coefficient and Mechanism of the OH-Initiated Degradation of 1-Chlorobutane: Atmospheric Implications.  |  Jara-Toro, RA., et al. 2020. J Phys Chem A. 124: 229-239. PMID: 31825215
  6. Tuning the porosity of triangular supramolecular adsorbents for superior haloalkane isomer separations.  |  Hua, B., et al. 2021. Chem Sci. 12: 12286-12291. PMID: 34603658
  7. Negative-mode ion mobility spectrometry-comparison of ion-molecule reactions and electron capture processes.  |  Budzyńska, E., et al. 2022. Anal Bioanal Chem. 414: 3719-3728. PMID: 35305117
  8. Vibrational Polaritons in Disordered Molecular Ensembles.  |  Cohn, B., et al. 2022. J Phys Chem Lett. 13: 8369-8375. PMID: 36043884
  9. Emission behavior and impact assessment of gaseous volatile compounds in two typical rural domestic waste landfills.  |  Li, P., et al. 2023. J Environ Manage. 325: 116659. PMID: 36335702
  10. Prediction of Mefenamic Acid Crystal Shape by Random Forest Classification.  |  Nakapraves, S., et al. 2022. Pharm Res. 39: 3099-3111. PMID: 36534313
  11. Quantification of olanzapine and its three metabolites by liquid chromatography-tandem mass spectrometry in human body fluids obtained from four deceased, and confirmation of the reduction from olanzapine N-oxide to olanzapine in whole blood in vitro.  |  Nozawa, H., et al. 2023. Forensic Toxicol.. PMID: 36997675
  12. Efficient Remediation of p-chloroaniline Contaminated Soil by Activated Persulfate Using Ball Milling Nanosized Zero Valent Iron/Biochar Composite: Performance and Mechanisms.  |  Guo, Z., et al. 2023. Nanomaterials (Basel). 13: PMID: 37177062
  13. Global Sensitivity Analysis in Life-Cycle Assessment of Early-Stage Technology using Detailed Process Simulation: Application to Dialkylimidazolium Ionic Liquid Production.  |  Baaqel, HA., et al. 2023. ACS Sustain Chem Eng. 11: 7157-7169. PMID: 37180025

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Chlorobutane, 200 ml

sc-397740
200 ml
$68.00