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1-Chloro-6-iodohexane (CAS 34683-73-3)

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Alternate Names:
Hexamethylene chloroiodide
CAS Number:
34683-73-3
Purity:
≥95%
Molecular Weight:
246.52
Molecular Formula:
C6H12ClI
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Chloro-6-iodohexane (1-CIH) is primarily used as a reagent in organic synthesis and has been used in a variety of scientific research applications. It has been employed in creating polymers, dyes, and various other substances. Moreover, it′s utilized in the synthesis of chiral compounds and in the study of stereoselectivity. 1-Chloro-6-iodohexane is a highly reactive compound and can interact with a variety of substrates, including alkenes, alkynes, and aryl halides. It can also be used as a catalyst in certain reactions, such as the Wittig reaction. 1-Chloro-6-iodohexane has been demonstrated to inhibit both the acetylcholinesterase enzyme, which regulates neurotransmitter release, and the lipoxygenase enzyme, involved in fatty acid metabolism.


1-Chloro-6-iodohexane (CAS 34683-73-3) References

  1. Chemoselective, regioselective, and E/Z-diastereoselective synthesis of 2-alkylidenetetrahydrofurans by sequential reactions of ambident dianions and monoanions.  |  Langer, P. and Bellur, E. 2003. J Org Chem. 68: 9742-6. PMID: 14656101
  2. Ancillary ligand functionalization of cyanide-bridged S = 6 Fe(III)4Ni(II)4 complexes for molecule-based electronics.  |  Li, D., et al. 2006. Inorg Chem. 45: 7569-71. PMID: 16961342
  3. Thermal reactions of methyl linoleate. II. The structure of aromatic C18 methyl esters.  |  Michael, WR. 1966. Lipids. 1: 359-64. PMID: 17805602
  4. Preparation of functionalized aryl iron(II) compounds and a nickel-catalyzed cross-coupling with alkyl halides.  |  Wunderlich, SH. and Knochel, P. 2009. Angew Chem Int Ed Engl. 48: 9717-20. PMID: 19924751
  5. Metal-Free Radical Borylation of Alkyl and Aryl Iodides.  |  Cheng, Y., et al. 2018. Angew Chem Int Ed Engl. 57: 16832-16836. PMID: 30332527
  6. Long-acting contraceptive agents: esters of norethisterone with alkoxy- and halogeno-substituted carboxylic acids.  |  Shafiee, A., et al. 1983. Steroids. 41: 285-90. PMID: 6658876
  7. Direct Reduction of 1-Bromo-6-chlorohexane and 1-Chloro-6-iodohexane at Silver Cathodes in Dimethylformamide  |  John A. Rose a, Caitlyn M. McGuire a, Angela M. Hansen a, Jonathan A. Karty a, Mohammad S. Mubarak b, Dennis G. Peters a. 10 November 2016,. Electrochimica Acta. Volume 218,: Pages 311-317.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Chloro-6-iodohexane, 10 g

sc-224620
10 g
$120.00