Date published: 2026-5-9

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1-Chloro-3-fluoro-2-propanol (CAS 453-11-2)

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Alternate Names:
1-Chloro-3-fluoroisopropanol
CAS Number:
453-11-2
Molecular Weight:
112.53
Molecular Formula:
C3H6ClFO
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Chloro-3-fluoro-2-propanol, also known as CF2OH, is a halohydrin compound used as a building block in organic synthesis. It has been employed in the synthesis of pesticides, polymers, polyvinyl chloride, polyurethane, and polystyrene. 1-Chloro-3-fluoro-2-propanol is an electrophilic reagent. Its reactivity is due to the presence of a halogen atom, which is highly electronegative and attracts electrons. The halogen atom also acts as a leaving group, allowing for a nucleophile to attack the carbon atom of the 1-Chloro-3-fluoro-2-propanol molecule.


1-Chloro-3-fluoro-2-propanol (CAS 453-11-2) References

  1. The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (-)-erythro-fluorocitrate.  |  Menon, KI., et al. 2001. J Biochem Mol Toxicol. 15: 47-54. PMID: 11170315
  2. The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote.  |  Feldwick, MG., et al. 1998. J Biochem Mol Toxicol. 12: 41-52. PMID: 9414486

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Chloro-3-fluoro-2-propanol, 5 g

sc-273280
5 g
$202.00