Date published: 2026-4-29

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1-Butylpiperazine (CAS 5610-49-1)

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Alternate Names:
1-(But-1-yl)piperazine
CAS Number:
5610-49-1
Purity:
≥97%
Molecular Weight:
142.24
Molecular Formula:
C8H18N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Butylpiperazine serves as a building block in organic synthesis. It is an important intermediate in the production of various medical compounds, agrochemicals, and other specialized chemicals. Its mechanism of action involves participating in nucleophilic substitution reactions, allowing for the introduction of the butylpiperazine moiety into complex molecular structures. This enables the modification of the physicochemical properties of target compounds, leading to the development of novel materials and compounds with diverse applications. At the molecular level, it interacts with other reagents and substrates to facilitate the formation of new chemical bonds, thereby playing a role in the construction of complex molecular architectures.


1-Butylpiperazine (CAS 5610-49-1) References

  1. The pH of Piperazine Derivative Solutions Predicts Their Utility as Transepithelial Permeation Enhancers.  |  Lamson, NG., et al. 2016. Mol Pharm. 13: 578-85. PMID: 26730955
  2. Design, synthesis, and in vitro and in vivo characterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H3 receptor antagonists.  |  Staszewski, M., et al. 2019. Medchemcomm. 10: 234-251. PMID: 30881612
  3. Amino Appended Coumarin Composites for Pb2+ Capturing in Aqueous Medium.  |  Sharma, N. and Gulati, A. 2022. J Fluoresc. 32: 109-114. PMID: 34586573
  4. Discovery of dual inhibitors of topoisomerase I and Cyclooxygenase-2 for colon cancer therapy.  |  Hu, X., et al. 2022. Eur J Med Chem. 240: 114560. PMID: 35777102
  5. Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers.  |  Yuan, XY., et al. 2023. Eur J Med Chem. 252: 115281. PMID: 36940611
  6. Characteristics of ignition delay of hypergolic ionic liquids combined with 1-amino-4-methylpiperazine.  |  Shin, KS., et al. 2023. RSC Adv. 13: 18960-18963. PMID: 37362602
  7. Vibrational spectra, DFT calculations, conformational stabilities and assignments of the fundamentals of the 1-butylpiperazine  |  Özge Bağlayan a, Mehmet Fatih Kaya b, Esma Güneş a, Mustafa Şenyel a. 2016. Journal of Molecular Structure. 1122: 324-330.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Butylpiperazine, 5 g

sc-224594
5 g
$54.00