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1-Butene oxide (CAS 106-88-7)

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Alternate Names:
1,2-Butylene oxide; Ethyloxirane; Ethylethylene oxide
Application:
1-Butene oxide is a hydrogen chloride acceptor in chlorocarbons
CAS Number:
106-88-7
Purity:
≥98%
Molecular Weight:
72.11
Molecular Formula:
C4H8O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Butene oxide, also known as butylene oxide or 1,2-epoxybutane, is a four-carbon epoxide with the molecular formula C4H8O. This organic compound features an ethylene oxide-like ring, specifically an oxygen atom bridging two adjacent carbon atoms, creating a three-membered ring structure that imparts significant strain and reactivity to the molecule. In chemical research, 1-butene oxide is primarily studied for its role as a reactive intermediate in the synthesis of a wide range of chemical products, including pharmaceuticals, polymers, and fine chemicals. The strained epoxide ring in 1-butene oxide is highly reactive and can undergo ring-opening reactions, which are facilitated either by acid or base catalysis, leading to the formation of diols, alcohols, and other oxygen-containing functional groups. This reactivity makes it valuable for creating complex molecular architectures through straightforward synthetic routes. Additionally, researchers utilize 1-butene oxide in the study of polymer chemistry, particularly in the production of polyethers and other epoxy-derived materials that require controlled ring-opening polymerization techniques to achieve desired properties like flexibility, resistance, and durability. The compound′s volatility and reactivity also make it a subject of safety and environmental impact studies, particularly regarding its behavior and effects when released into the atmosphere.


1-Butene oxide (CAS 106-88-7) References

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  3. Enantioselective polymerization of epoxides: a highly active and selective catalyst for the preparation of stereoregular polyethers and enantiopure epoxides.  |  Hirahata, W., et al. 2008. J Am Chem Soc. 130: 17658-9. PMID: 19067512
  4. Mechanistic Insights into the Alternating Copolymerization of Epoxides and Cyclic Anhydrides Using a (Salph)AlCl and Iminium Salt Catalytic System.  |  Fieser, ME., et al. 2017. J Am Chem Soc. 139: 15222-15231. PMID: 28984455
  5. All-Polycarbonate Thermoplastic Elastomers Based on Triblock Copolymers Derived from Triethylborane-Mediated Sequential Copolymerization of CO2 with Various Epoxides.  |  Jia, M., et al. 2020. Macromolecules. 53: 5297-5307. PMID: 32905284
  6. Respiratory tract lesions in F344/N rats and B6C3F1 mice after inhalation exposure to 1,2-epoxybutane.  |  Dunnick, JK., et al. 1988. Toxicology. 50: 69-82. PMID: 3388431
  7. Perfectly Alternating Copolymerization of Cyclic Anhydrides and Epoxides with Yttrium β-Diketiminate Complexes.  |  Manjarrez, Y., et al. 2022. Inorg Chem. 61: 7088-7094. PMID: 35483671
  8. Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice.  |  Henschler, D., et al. 1984. J Cancer Res Clin Oncol. 107: 149-56. PMID: 6736101
  9. Use of rat/hamster S-9 mixture in the Ames mutagenicity assay.  |  Weinstein, D., et al. 1981. Environ Mutagen. 3: 1-9. PMID: 7021141
  10. Polyneuropathy due to ethylene oxide, propylene oxide, and butylene oxide.  |  Ohnishi, A. and Murai, Y. 1993. Environ Res. 60: 242-7. PMID: 8472653

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Butene oxide, 250 ml

sc-224584
250 ml
$36.00