1-Boc-4-bromopiperidine (CAS 180695-79-8)
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1-Boc-4-bromopiperidine is a chemical compound that functions as a versatile building block in organic synthesis. It serves as a key intermediate in the preparation of various agrochemicals and other fine chemicals. It participates in a range of transformations, including cross-coupling reactions, nucleophilic substitution, and palladium-catalyzed coupling reactions. 1-Boc-4-Bromopiperidine′s functional role lies in its ability to undergo selective functionalization at the bromine position, allowing for the introduction of diverse chemical functionalities. This enables the synthesis of structurally diverse compounds with potential biological activity. Its mechanism of action involves facilitating the creation of novel chemical entities with potential applications in various fields of chemical and biological research.
1-Boc-4-bromopiperidine (CAS 180695-79-8) References
- Reductive cross-coupling of nonaromatic, heterocyclic bromides with aryl and heteroaryl bromides. | Molander, GA., et al. 2014. J Org Chem. 79: 5771-80. PMID: 24892751
- Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives. | Bazin, HG., et al. 2015. Bioorg Med Chem Lett. 25: 1318-23. PMID: 25698055
- Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion. | Park, JH., et al. 2016. J Med Chem. 59: 7410-30. PMID: 27427902
- Bis-enolates with Extended π-Conjugation Are Powerful Nucleophiles: A Study of Their Alkylation Reactions with Very Hindered C-Electrophiles. | Castroagudín, M., et al. 2019. J Org Chem. 84: 15805-15816. PMID: 31778066
- Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7. | Kovalová, M., et al. 2023. Biomed Pharmacother. 161: 114492. PMID: 36931035
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Boc-4-bromopiperidine, 1 g | sc-229773D | 1 g | $13.00 | |||
1-Boc-4-bromopiperidine, 5 g | sc-229773 | 5 g | $41.00 | |||
1-Boc-4-bromopiperidine, 25 g | sc-229773A | 25 g | $163.00 | |||
1-Boc-4-bromopiperidine, 100 g | sc-229773B | 100 g | $571.00 | |||
1-Boc-4-bromopiperidine, 500 g | sc-229773C | 500 g | $2295.00 |