1-Boc-4-aminopiperidine-4-carboxylic Acid (CAS 183673-71-4)
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1-Boc-4-aminopiperidine-4-carboxylic Acid is a chemical compound utilized as a building block in organic synthesis. In research, it is particularly useful for the synthesis of peptide and peptidomimetic molecules due to the presence of both amine and carboxylic acid functional groups. The Boc (tert-butoxycarbonyl) group serves as a protective group for the amine, allowing for selective reactions to occur at other sites of the molecule without interference. This feature is critical for stepwise construction of complex molecules in combinatorial chemistry. Additionally, the piperidine ring is a common structural motif in many biologically active compounds, and thus 1-Boc-4-aminopiperidine-4-carboxylic Acid is used to explore various aspects of medicinal chemistry. It also finds application in the study of amide bond formation techniques and the optimization of coupling conditions in peptide synthesis.
1-Boc-4-aminopiperidine-4-carboxylic Acid (CAS 183673-71-4) References
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- Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides. | Fattori, D., et al. 2006. J Med Chem. 49: 3602-13. PMID: 16759102
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Boc-4-aminopiperidine-4-carboxylic Acid, 1 g | sc-220465 | 1 g | $134.00 |