Molecular structure of 1-Benzhydrylazetidin-3-ol, CAS Number: 18621-17-5
1-Benzhydrylazetidin-3-ol (CAS 18621-17-5)
Alternate Names:
1-(Diphenylmethyl)-3-hydroxyazetinide; 1-(Diphenylmethyl)-3-azetidinol; 1-(Diphenylmethyl)-3-azetidinol; NSC 319045;
Application:
1-Benzhydrylazetidin-3-ol is used in the identification of CYP 3A4 inhibitors
CAS Number:
18621-17-5
Molecular Weight:
239.31
Molecular Formula:
C16H17NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Used in the identification of CYP 3A4 inhibitors.
1-Benzhydrylazetidin-3-ol (CAS 18621-17-5) References
- 3-((Hetera)cyclobutyl)azetidines, 'Stretched' Analogues of Piperidine, Piperazine, and Morpholine: Advanced Building Blocks for Drug Discovery. | Feskov, IO., et al. 2019. J Org Chem. 84: 1363-1371. PMID: 30583694
- Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. | Malamas, MS., et al. 2020. Bioorg Med Chem. 28: 115195. PMID: 31761726
- Divergent dehydroxyfluorination and carbonation of alcohols with trifluoromethyl trifluoromethanesulfonate. | Ran, LY., et al. 2023. Org Biomol Chem. 21: 1235-1241. PMID: 36633208
- Enantioselective Synthesis of Axially Chiral Diaryl Ethers via NHC Catalyzed Desymmetrization and Following Resolution. | Zhou, BA., et al. 2024. Angew Chem Int Ed Engl. 63: e202314228. PMID: 38019184
- Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. | Burke, MD., et al. 1985. Biochem Pharmacol. 34: 3337-45. PMID: 3929792
- Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput. | Berman, J., et al. 1997. J Med Chem. 40: 827-9. PMID: 9083469
- An efficient two-step synthesis of 3-amino-1-benzhydrylazetidine | Li, B., Witt, M. F., Brandt, T. A., & Whritenour, D. 2006. journal of Chemical Research. 2006(7): 478-480.
- Improved Process for the Preparation of 1-Benzhydrylazetidin-3-ol: Development of an Efficient Synthesis and Identification of Process-related Impurities and/or Intermediates | Reddy, V. K., Babu, K. K., Ganesh, A., Srinivasulu, P., Madhusudhan, G., & Mukkanti, K. 2010. Organic Process Research & Development. 14(4): 931-935.
- Development of an optimized process for the preparation of 1-benzylazetidin-3-ol: an industrially important intermediate for substituted azetidine | Krishna Reddy, V. V. R. M., Udaykiran, D., Chintamani, U. S., Mahesh Reddy, E., Kameswararao, C., & Madhusudhan, G. 2011. Organic Process Research & Development. 15(2): 462-466.
- Molecular characteristics of 1-benzhydrylazetidin-3-ol by time-dependent density functional theory analysis | Ravindranath, L., Rao, P. V. R., Srishailam, K., & Reddy, B. V. 2023. Materials Today: Proceedings. 92: 1023-1029.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Benzhydrylazetidin-3-ol, 2 g | sc-220460 | 2 g | $330.00 |