Date published: 2026-4-30

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1-Aza-15-crown-5 (CAS 66943-05-3)

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Alternate Names:
1,4,7,10-Tetraoxa-13-azacyclopentadecane
CAS Number:
66943-05-3
Molecular Weight:
219.28
Molecular Formula:
C10H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Aza-15-crown-5 is a macrocyclic compound that is widely used in research for its ability to act as a ligand in coordination chemistry. As a member of the azacrown ether family, this compound is characterized by its ring structure containing both ether and amine linkages. The presence of the nitrogen atom within the macrocycle gives 1-Aza-15-crown-5 distinctive complexation properties, particularly towards metal ions. In studies of host-guest chemistry, researchers explore how 1-Aza-15-crown-5 selectively binds to certain cations, which can be useful for understanding ion transport mechanisms and developing ion-selective sensors. Moreover, this compound is investigated for its use in facilitating organic synthesis reactions through the formation of complexes that can stabilize reactive intermediates or catalyze specific transformations. Its application in the design of supramolecular assemblies is also of interest, where its binding properties can lead to the formation of novel materials with specific functionalities.


1-Aza-15-crown-5 (CAS 66943-05-3) References

  1. Spectroscopic studies of complexes of iodine with the bases 1-aza-15-crown-5 and 3,6,9,14-tetrathiabicyclo[9.2.1]tetradeca-11,13-diene.  |  Hassan, KhA. 2004. Spectrochim Acta A Mol Biomol Spectrosc. 60: 3059-63. PMID: 15477144
  2. meso-(4-(N,N-dialkylamino)phenyl)-substituted subporphyrins: remarkably perturbed absorption spectra and enhanced fluorescence by intramolecular charge transfer interactions.  |  Inokuma, Y., et al. 2008. J Am Chem Soc. 130: 12234-5. PMID: 18720986
  3. Fluorescent properties of an azacrown-containing styryl derivative of naphthopyran: ion-binding response and photochemical switching off.  |  Smolentsev, AB., et al. 2013. Photochem Photobiol Sci. 12: 1803-10. PMID: 23835791
  4. Nonlinear optical chemosensor for sodium ion based on rhodol chromophore.  |  Poronik, YM., et al. 2013. J Org Chem. 78: 11721-32. PMID: 24245744
  5. 1-Aza-15-Crown-5 Functionalized Graphene Oxide for 2D Graphene-Based Li⁺-ion Conductor.  |  Banerjee, M., et al. 2015. Small. 11: 3451-7. PMID: 25757440
  6. Solvate and protic ionic liquids from aza-crown ethers: synthesis, thermal properties, and LCST behavior.  |  Oba, Y., et al. 2018. Phys Chem Chem Phys. 20: 3118-3127. PMID: 28849817
  7. Pyrroloquinoline Quinone Aza-Crown Ether Complexes as Biomimetics for Lanthanide and Calcium Dependent Alcohol Dehydrogenases*.  |  Vetsova, VA., et al. 2021. Chemistry. 27: 10087-10098. PMID: 33872420
  8. Luminescent Pt(II) Complexes Containing (1-Aza-15-crown-5)dithiocarbamate and (1-Aza-18-crown-6)dithiocarbamate: Mechanochromic and Solvent-Induced Luminescence.  |  Tzeng, BC., et al. 2023. Inorg Chem. 62: 916-929. PMID: 36584668

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Aza-15-crown-5, 1 g

sc-237467
1 g
$145.00