Molecular structure of 1-Aminocyclopentanecarboxylic acid, CAS Number: 52-52-8
1-Aminocyclopentanecarboxylic acid (CAS 52-52-8)
Alternate Names:
Cycloleucine
Application:
1-Aminocyclopentanecarboxylic acid is an NMDA receptor antagonist at the glycine site
CAS Number:
52-52-8
Molecular Weight:
129.16
Molecular Formula:
C6H11NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Aminocyclopentanecarboxylic acid is an NMDA receptor antagonist acting at the glycine site.
1-Aminocyclopentanecarboxylic acid (CAS 52-52-8) References
- Cadmium inhibition of basolateral solute fluxes in rabbit renal tubules and the nature of cycloleucine uptake. | Foulkes, EC. and Blanck, S. 1991. Toxicol Appl Pharmacol. 108: 150-6. PMID: 2006502
- In vitro transport of cycloleucine by equine cecal mucosa. | Freeman, DE. and Donawick, WJ. 1991. Am J Vet Res. 52: 539-42. PMID: 2053721
- Cycloleucine blocks 5'-terminal and internal methylations of avian sarcoma virus genome RNA. | Dimock, K. and Stolzfus, CM. 1978. Biochemistry. 17: 3627-32. PMID: 210799
- 1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor. | Hood, WF., et al. 1989. Eur J Pharmacol. 161: 281-2. PMID: 2542048
- Effects of Cycloleucine in the Nucleus Accumbens Septi on the Elevated plus Maze Test in Rats. | Gargiulo, API., et al. 2020. Neuropsychobiology. 79: 191-197. PMID: 31927553
- Transcriptome analysis of the inhibitory effect of cycloleucine on myogenesis. | Wang, Z., et al. 2022. Poult Sci. 101: 102219. PMID: 36308813
- Effects of exogenous glycine betaine and cycloleucine on photosynthetic capacity, amino acid composition, and hormone metabolism in Solanum melongena L. | Niu, T., et al. 2023. Sci Rep. 13: 7626. PMID: 37165051
- Steady-state distribution of cycloleucine and alpha-aminoisobutyric acid between plasma and cerebrospinal fluid. | Davson, H., et al. 1986. Exp Neurol. 91: 163-73. PMID: 3940873
- Handguns and homicide. | . 1977. JAMA. 237: 1558-9. PMID: 576650
- Effect of cycloleucine on amino acid accumulation by human diploid fibroblasts. | Moatti, N., et al. 1978. Clin Chim Acta. 86: 245-9. PMID: 668116
- Experimental cystinuria: the cycloleucine model. II. Amino acid efflux from intestinal and renal tissues. | Craan, AG. and Bergeron, M. 1978. Metabolism. 27: 1613-25. PMID: 703604
- Phase II study of high-dose intermittent cycloleucine in colorectal malignancies. | Dindogru, A., et al. 1982. Cancer Treat Rep. 66: 203-4. PMID: 7053260
- Cycloleucine uptake in the brainstem of thiamine-deficient rats. | Manz, HJ., et al. 1976. Acta Neuropathol. 36: 47-56. PMID: 970113
Inhibitor of:
AGAT, APIP, BHMT2, C8orf79_6430573F11Rik, KIAA1429, MAT Iα, MAT IIα, MAT IIβ, METTL2B, NMDA, NSUN3, TRM61, TRMT5, Y+LAT1, YT521-B, and YTHDF2.Activator of:
FTSJ3, SLC7A6, and THNSL2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Aminocyclopentanecarboxylic acid, 1 g | sc-202392 | 1 g | $23.00 |