Molecular structure of 1-Aminoacetone Hydrochloride, CAS Number: 7737-17-9
1-Aminoacetone Hydrochloride (CAS 7737-17-9)
Alternate Names:
1-aminopropan-2-one hydrochloride
Application:
1-Aminoacetone Hydrochloride is a threonine and glycine catabolite converted to methylglyoxal by amine oxidases
CAS Number:
7737-17-9
Purity:
≥96%
Molecular Weight:
109.55
Molecular Formula:
C3H8ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Aminoacetone Hydrochloride is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. As a pro-oxidant, 0.10-5 mM 1-Aminoacetone can induce cell death in RINm5f pancreatic beta-cells. 1-Aminoacetone is used as a growth substrate for Pseudomonas. This compound is characterized by the presence of both an amino group and a ketone functional group within its molecular structure, making it a versatile building block for the formation of more complex molecules. The incorporation of the hydrochloride salt enhances its solubility in aqueous solutions, facilitating its handling and reactivity in chemical reactions.
1-Aminoacetone Hydrochloride (CAS 7737-17-9) References
- Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors. | Borzilleri, RM., et al. 2005. J Med Chem. 48: 3991-4008. PMID: 15943473
- Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death to insulin-producing RINm5f cells. | Sartori, A., et al. 2008. Chem Res Toxicol. 21: 1841-50. PMID: 18729331
- Tetrahydrochromenoimidazoles as potassium-competitive acid blockers (P-CABs): structure-activity relationship of their antisecretory properties and their affinity toward the hERG channel. | Palmer, AM., et al. 2010. J Med Chem. 53: 3645-74. PMID: 20380432
- Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. | Husain, A., et al. 2010. J Biol Chem. 285: 39160-70. PMID: 20923776
- Acid active receptor-specific peptide ligand for in vivo tumor-targeted delivery. | Han, L., et al. 2013. Small. 9: 3647-58. PMID: 23649993
- Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new three-domain family of bacterial flavoproteins. | Molla, G., et al. 2014. Biochem J. 464: 387-99. PMID: 25269103
- Aminoacetone formation and utilization by pseudomonads grown on DL-1-aminopropan-2-ol. | Higgins, IJ., et al. 1968. J Gen Microbiol. 54: 105-14. PMID: 5729603
- Formation of methylglyoxal from aminoacetone by amine oxidase from goat plasma. | Ray, S. and Ray, M. 1983. J Biol Chem. 258: 3461-2. PMID: 6833209
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Aminoacetone Hydrochloride, 50 mg | sc-208603 | 50 mg | $255.00 |