Molecular structure of 1-Allyl-3,7-dimethyl-8-phenylxanthine, CAS Number: 149981-23-7
1-Allyl-3,7-dimethyl-8-phenylxanthine (CAS 149981-23-7)
Application:
1-Allyl-3,7-dimethyl-8-phenylxanthine is an A1 adenosine receptor antagonist
CAS Number:
149981-23-7
Purity:
≥95%
Molecular Weight:
296.32
Molecular Formula:
C16H16N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Allyl-3,7-dimethyl-8-phenylxanthine is an antagonist of the Adenosine A1-R (A1 adenosine receptor). 1-Allyl-3,7-dimethyl-8-phenylxanthine is described to block increases in intracellular Ca2+ concentration produced by the A1 receptor agonist 2-chloro-N6-cyclopentyl-adenosine but did not antagonize increases produced by the A2 agonist 2-p-(2-carboxy-ethyl) phenethylamino-5'-N-ethylcarboxyamide adenosine hydrochloride or the A3 agonist N6-2-(4-Aminophenyl)ethyladenosine (sc-253170).
1-Allyl-3,7-dimethyl-8-phenylxanthine (CAS 149981-23-7) References
- Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs. | Jiang, X., et al. 2000. Int J Oncol. 16: 971-8. PMID: 10762633
- Traceless solid-phase synthesis of substituted xanthines. | He, R., et al. 2006. J Comb Chem. 8: 923-8. PMID: 17096582
- Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. | Jacobson, KA., et al. 1993. J Med Chem. 36: 2639-44. PMID: 8410976
- Development of predictive models by adaptive fuzzy partitioning. Application to compounds active on the central nervous system | Ros, F., Taboureau, O., Pintore, M., & Chretien, J. R. 2003. Chemometrics and intelligent laboratory systems. 67(1): 29-50.
Inhibitor of:
Adenosine A1-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Allyl-3,7-dimethyl-8-phenylxanthine, 25 mg | sc-206125 | 25 mg | $170.00 |