Molecular structure of 1-Acyl-PAF, CAS Number: 84062-61-3
1-Acyl-PAF (CAS 84062-61-3)
Alternate Names:
1-O-Palmitoyl-2-O-acetyl-sn-glycero-3-phosphorylcholine;1-Palmitoyl-2-acetyl-gpc;PAGPC
Application:
1-Acyl-PAF is a platelet activating factor that induces IL-6 release in rat anterior pituitary cells
CAS Number:
84062-61-3
Purity:
≥98%
Molecular Weight:
537.67
Molecular Formula:
C26H52NO8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Acyl-PAF is the predominant PAF species produced by stimulated endothelial cells1,2. This compound induces IL-6 release in rat anterior pituitary cells in vitro and the compound also displays protective effects in oxidative stress.
1-Acyl-PAF (CAS 84062-61-3) References
- Influence of platelet-activating factor, its cell analogs, and antagonist on the production of superoxide radicals by blood leukocytes of healthy and hypercholesterolemic individuals. | Kulikov, VI. and Muzya, GI. 2002. Biochemistry (Mosc). 67: 662-6. PMID: 12126473
- Influence of acyl and plasmalogenic analogs of platelet activating factor on chemotaxis of human leukocytes in vitro and their inflammatory and antiinflammatory activity in vivo. | Kulikov, VI. and Muzya, GI. 2002. Biochemistry (Mosc). 67: 1248-52. PMID: 12495421
- Modulation by flavonoids of PAF and related phospholipids in endothelial cells during oxidative stress. | Balestrieri, ML., et al. 2003. J Lipid Res. 44: 380-7. PMID: 12576520
- Differential responsiveness of human neutrophils to the autocrine actions of 1-O-alkyl-homologs and 1-acyl analogs of platelet-activating factor. | Pinckard, RN., et al. 1992. J Immunol. 148: 3528-35. PMID: 1316919
- Relative amounts of 1-O-alkyl- and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in stimulated endothelial cells. | Whatley, RE., et al. 1992. Prostaglandins. 43: 21-9. PMID: 1546171
- The metabolism of 1-acyl-PAF in rabbit platelets and its possible interaction with PAF. | Touqui, L., et al. 1991. Lipids. 26: 992-6. PMID: 1819755
- Synthesis of 1-acyl-2-[3H]acetyl-SN-glycero-3-phosphocholine, a structural analog of platelet activating factor, by vascular endothelial cells. | Mueller, HW., et al. 1991. Biochem Biophys Res Commun. 176: 1557-64. PMID: 2039529
- [Biological role of cellular metabolites--structural analogs of platelet activating factor]. | Kulikov, VI. and Muzia, GI. 1996. Biokhimiia. 61: 387-403. PMID: 8724598
- Platelet-activating factor biosynthesis induced by various stimuli in human HaCaT keratinocytes. | Travers, JB., et al. 1996. J Invest Dermatol. 107: 88-94. PMID: 8752845
- Lysophosphatidylcholine stimulates interleukin-6 release from rat anterior pituitary cells in vitro. | Spangelo, BL. and Jarvis, WD. 1996. Endocrinology. 137: 4419-26. PMID: 8828503
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Acyl-PAF, 1 mg | sc-205565 | 1 mg | $67.00 | |||
1-Acyl-PAF, 5 mg | sc-205565A | 5 mg | $233.00 |