Date published: 2026-2-19

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1,5-Diacetylindoline (CAS 16078-35-6)

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Alternate Names:
1,1′-(Indoline-1,5-diyl)diethanone
CAS Number:
16078-35-6
Molecular Weight:
203.24
Molecular Formula:
C12H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,5-Diacetylindoline is a chemical compound that functions as a reactant in various organic synthesis reactions. It acts as a precursor in the formation of indole derivatives, which are important building blocks in the synthesis of agrochemicals and materials. In the experimental, 1,5-Diacetylindoline participates in condensation reactions with other reagents to form complex organic molecules with potential biological activity. Its mechanism of action involves undergoing nucleophilic addition and subsequent cyclization to form the desired indole products. 1,5-Diacetylindoline′s role in the laboratory setting is to facilitate the creation of diverse molecular structures for further investigation and potential application in various fields of development.


1,5-Diacetylindoline (CAS 16078-35-6) References

  1. Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)  |  Axten, J. M., Medina, J. R., Feng, Y., Shu, A., Romeril, S. P., Grant, S. W.,.. & Gampe, R. T. 2012. Journal of medicinal chemistry. 55(16): 7193-7207.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,5-Diacetylindoline, 1 g

sc-223074
1 g
$75.00