Molecular structure of 1,5-Anhydro-D-sorbitol, CAS Number: 154-58-5
1,5-Anhydro-D-sorbitol (CAS 154-58-5)
Alternate Names:
1,5-Anhydro-D-glucitol
Application:
1,5-Anhydro-D-sorbitol is a cyclic polyol and metabolic product of 1,5 anhydro-D-fructose
CAS Number:
154-58-5
Molecular Weight:
164.16
Molecular Formula:
C6H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,5-Anhydro-D-sorbitol, a cyclic polyol, is a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-glucitol is recognized for its ability to function as an inhibitor of the enzyme aldose reductase, which plays a role in controlling glucose metabolism. The primary effect of inhibiting aldose reductase with 1,5-Anhydro-D-glucitol is believed to be the mitigation of advanced glycation end products (AGEs) buildup.
1,5-Anhydro-D-sorbitol (CAS 154-58-5) References
- Quantification of myo-inositol, 1,5-anhydro- D-sorbitol, and D-chiro-inositol using high-performance liquid chromatography with electrochemical detection in very small volume clinical samples. | Schimpf, KJ., et al. 2015. Biomed Chromatogr. 29: 1629-36. PMID: 26010453
- Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes. | Giesbertz, P., et al. 2015. Diabetologia. 58: 2133-43. PMID: 26058503
- New Nordic Diet versus Average Danish Diet: A Randomized Controlled Trial Revealed Healthy Long-Term Effects of the New Nordic Diet by GC-MS Blood Plasma Metabolomics. | Khakimov, B., et al. 2016. J Proteome Res. 15: 1939-54. PMID: 27146725
- Kinetic analyses of intramolecular dehydration of hexitols in high-temperature water. | Yamaguchi, A., et al. 2020. Carbohydr Res. 487: 107880. PMID: 31785566
- Serum metabolomics reveals metabolic profiling for women with hyperandrogenism and insulin resistance in polycystic ovary syndrome. | Zhang, Z., et al. 2020. Metabolomics. 16: 20. PMID: 31980950
- Characterization of Short-Term Heat Stress in Holstein Dairy Cows Using Altered Indicators of Metabolomics, Blood Parameters, Milk MicroRNA-216 and Characteristics. | Jo, JH., et al. 2021. Animals (Basel). 11: PMID: 33800868
- Heat Stress: Effects on Rumen Microbes and Host Physiology, and Strategies to Alleviate the Negative Impacts on Lactating Dairy Cows. | Kim, SH., et al. 2022. Front Microbiol. 13: 804562. PMID: 35295316
- Plasma Metabolites and Gut Microbiota Are Associated With T cell Imbalance in BALB/c Model of Eosinophilic Asthma. | Zhou, Y., et al. 2022. Front Pharmacol. 13: 819747. PMID: 35662725
- Guominkang formula alleviate inflammation in eosinophilic asthma by regulating immune balance of Th1/2 and Treg/Th17 cells. | Zhou, Y., et al. 2022. Front Pharmacol. 13: 978421. PMID: 36330091
- Metabolomics profiling in predicting of post-herpetic neuralgia induced by varicella zoster. | Lu, L., et al. 2023. Sci Rep. 13: 14940. PMID: 37697028
Inhibitor of:
Enzyme, and NAGS.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,5-Anhydro-D-sorbitol, 100 mg | sc-216143 | 100 mg | $292.00 | |||
1,5-Anhydro-D-sorbitol, 1 g | sc-216143A | 1 g | $423.00 | |||
1,5-Anhydro-D-sorbitol, 2 g | sc-216143B | 2 g | $649.00 | |||
1,5-Anhydro-D-sorbitol, 5 g | sc-216143C | 5 g | $1025.00 |