1,4:3,6-Dianhydro-D-mannitol (CAS 641-74-7)

1,4:3,6-Dianhydro-D-mannitol, also known as isomannide, is a bicyclic sugar alcohol derived from D-mannitol, featuring two anhydro bridges between hydroxyl groups. This unique structure imparts rigidity and stability, making it a valuable compound in carbohydrate chemistry and material science research. In biochemical studies, 1,4:3,6-Dianhydro-D-mannitol is used to investigate the stereochemical aspects of enzymatic reactions, particularly those involving glycosidases and epimerases. Its rigid structure serves as a model substrate for studying the mechanisms of these enzymes and their specific interactions with cyclic and anhydro sugar derivatives. Researchers have utilized 1,4:3,6-Dianhydro-D-mannitol in the synthesis of novel polymeric materials, exploring its potential as a monomer for biodegradable polymers. Its anhydro bridges provide sites for chemical modifications, enabling the creation of polymers with diverse properties and applications. This compound also plays a role in studying the conformational properties of sugar alcohols and their derivatives, contributing to the understanding of their behavior in solution and solid states. Moreover, 1,4:3,6-Dianhydro-D-mannitol is employed in the development of chiral catalysts and ligands for asymmetric synthesis, taking advantage of its well-defined stereochemistry. Overall, this compound is a versatile tool in advancing the fields of carbohydrate chemistry, enzymology, and material science, offering insights into enzyme mechanisms, polymer development, and stereochemical applications.