Date published: 2025-10-19

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1-[4-(Trifluoromethyl)benzyl]piperazine (CAS 107890-32-4)

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Alternate Names:
1-[[4-(trifluoromethyl)phenyl]methyl]piperazine
CAS Number:
107890-32-4
Purity:
≥96%
Molecular Weight:
244.26
Molecular Formula:
C12H15F3N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-[4-(Trifluoromethyl)benzyl]piperazine, in the synthesis and functionalization of piperazine derivatives, 1-[4-(Trifluoromethyl)Benzyl]Piperazine is important for studies on the interaction between piperazine structures and various biological targets, providing insights into the design of molecules with potential biological activity. In materials science, 1-[4-(Trifluoromethyl)benzyl]piperazine is investigated for its role in the creation of new polymeric materials that incorporate piperazine units, which can enhance material properties such as flexibility and thermal stability. 1-[4-(Trifluoromethyl)benzyl]piperazine serves as a precursor in the preparation of complex organic molecules that require the incorporation of trifluoromethyl and benzyl groups. 1-[4-(Trifluoromethyl)benzyl]piperazine, explored the Mechanisms of Molecular Interactions in the Development of Sensors and Other Detection Systems.


1-[4-(Trifluoromethyl)benzyl]piperazine (CAS 107890-32-4) References

  1. Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors.  |  Cao, J., et al. 2016. J Med Chem. 59: 10676-10691. PMID: 27933960
  2. Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.  |  Rohde, JM., et al. 2018. Bioorg Med Chem. 26: 1727-1739. PMID: 29555419
  3. Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach.  |  Gupta, Y., et al. 2021. Bioorg Med Chem. 47: 116393. PMID: 34509862
  4. The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.  |  Gupta, Y., et al. 2022. Pharmaceutics. 14: PMID: 35890267

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-[4-(Trifluoromethyl)benzyl]piperazine, 1 g

sc-229751
1 g
$49.00

1-[4-(Trifluoromethyl)benzyl]piperazine, 5 g

sc-229751A
5 g
$187.00