Molecular structure of 1-(4-Fluorophenyl)piperazine, CAS Number: 2252-63-3
1-(4-Fluorophenyl)piperazine (CAS 2252-63-3)
Alternate Names:
4-(1-Piperazinyl)fluorobenzene
Application:
1-(4-Fluorophenyl)piperazine is a metabolite of Niaparazine
CAS Number:
2252-63-3
Purity:
≥98%
Molecular Weight:
180.22
Molecular Formula:
C10H13FN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-(4-Fluorophenyl)piperazine is a metabolite of Niaparazine. This cyclic compound features a phenyl ring connected to a piperazine ring and serves as a starting material in the synthesis of diverse compounds. It is thought to function as an inhibitor for specific enzymes, including monoamine oxidase and the 5-HT2A receptor.
1-(4-Fluorophenyl)piperazine (CAS 2252-63-3) References
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- Benzimidazolone-based selective σ2 receptor ligands: Synthesis and pharmacological evaluation. | Intagliata, S., et al. 2019. Eur J Med Chem. 165: 250-257. PMID: 30685525
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- Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors. | Tugrak, M., et al. 2019. Bioorg Chem. 90: 103095. PMID: 31288135
- Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis. | Romagnoli, R., et al. 2022. Eur J Med Chem. 231: 114147. PMID: 35114540
- An optimised gas chromatographic-mass spectrometric method for the chemical characterisation of benzylpiperazine and 1-arylpiperazine based drugs | Kuleya, C., Hall, S., Gautam, L., & Cole, M. D. 2014. Analytical Methods. 6(1): 156-163.
- Synthesis and antimicrobial activities of hybrid heterocyclic molecules based on 1-(4-fluorophenyl) piperazine skeleton | Ozdemir, S. B., Demirbas, N., Cebeci, Y. U., Bayrak, H., Mermer, A., Ceylan, S., & Demirbas, A. 2017. Letters in Drug Design & Discovery. 14(9): 1014-1034.
- Design, Microwave‐Assisted and Conventional Synthesis of New Hybrid Compounds Derived From 1‐(4‐Fluorophenyl) piperazine and Screening for Their Biological Activities | Ozdemir, S. B., Demirbas, N., Demirbas, A., Colak, N., & Ayaz, F. A. 2018. ChemistrySelect. 3(7): 2144-2151.
- Synthesis and structural elucidation of novel antifungal N-(fluorophenyl) piperazinyl benzoxaboroles and their analogues | Borys, K. M., Matuszewska, A., Wieczorek, D., Kopczyńska, K., Lipok, J., Madura, I. D., & Adamczyk-Woźniak, A. 2019. Journal of Molecular Structure. 1181: 587-598.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-(4-Fluorophenyl)piperazine, 10 g | sc-255747 | 10 g | $62.00 |