Date published: 2026-4-23

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1,4-Dinitrosopiperazine (CAS 140-79-4)

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Alternate Names:
DNP; N,N′-Dinitrosopiperazine
Application:
1,4-Dinitrosopiperazine is induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium
CAS Number:
140-79-4
Molecular Weight:
144.13
Molecular Formula:
C4H8N4O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,4-Dinitrosopiperazine is actively utilized in experimental focused on properties of nitroso compounds and their derivatives. 1,4-Dinitrosopiperazine is studied for its role as a cross-linking agent, which is useful in understanding the polymerization processes in chemistry. In environmental chemistry, 1,4-Dinitrosopiperazine is used to study the stability and degradation pathways of nitroso compounds, which are critical for assessing environmental toxicity and degradation mechanisms. Also use 1,4-Dinitrosopiperazine to explore its interactions with biological molecules, providing insights into the potential effects of similar structures in biological systems. 1,4-Dinitrosopiperazine serves as a model compound in computational chemistry for simulating and predicting the behavior of chemically similar nitroso compounds in various conditions.


1,4-Dinitrosopiperazine (CAS 140-79-4) References

  1. A study of tobacco carcinogenesis. XIV. Effects of N'-nitrosonornicotine and N'-nitrosonanabasine in rats.  |  Hoffmann, D., et al. 1975. J Natl Cancer Inst. 55: 977-81. PMID: 1237631
  2. Chronic oral administration of 1-nitrosopiperazine at high doses to MRC rats.  |  Love, LA., et al. 1977. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 89: 69-73. PMID: 141802
  3. Comparative in vitro toxicity of nitrosamines and nitramines associated with amine-based carbon capture and storage.  |  Wagner, ED., et al. 2014. Environ Sci Technol. 48: 8203-11. PMID: 24940705
  4. [Renal excretion of 1,4-dinitrosopiperazine in dogs as an indication of nitrosamine formation in vivo (author's transl)].  |  Sander, J., et al. 1973. Hoppe Seylers Z Physiol Chem. 354: 384-90. PMID: 4803483
  5. Comparative light and scanning electron microscopic observations of nasal cavity carcinogenesis in rats treated with 1,4-dinitrosopiperazine.  |  Tsuda, H., et al. 1984. J Cancer Res Clin Oncol. 108: 186-91. PMID: 6470025
  6. Sequential changes in tumor development induced by 1,4-dinitrosopiperazine in the nasal cavity of F344 rats.  |  Takano, T., et al. 1982. Cancer Res. 42: 4236-40. PMID: 7105017
  7. Long-term feeding study in C17 mice administered saccharin coated betel nut and 1,4-dinitrosopiperazine in combination.  |  Pai, SR., et al. 1981. Carcinogenesis. 2: 175-7. PMID: 7273302
  8. Carcinogenic effects in rats of nitrosopiperazines administered intravesically: possible implications for the use of piperazine.  |  Lijinsky, W. and Kovatch, RM. 1993. Cancer Lett. 74: 101-3. PMID: 8287362

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,4-Dinitrosopiperazine, 1 g

sc-208792
1 g
$357.00