Date published: 2026-5-3

1-800-457-3801

SCBT Portrait Logo
Seach Input

1,4-Diisocyanatobutane (CAS 4538-37-8)

0.0(0)
Write a reviewAsk a question

CAS Number:
4538-37-8
Molecular Weight:
140.14
Molecular Formula:
C6H8N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

1,4-Diisocyanatobutane, also known as 1,4-DIB, is an extremely reactive organic compound that has numerous industrial uses. Its main function is in the creation of polyurethanes, polyureas, and other polymers. Beyond that, 1,4-Diisocyanatobutane is employed in the creation of substances used in agriculture, and various other chemical compounds. This compound is a colorless liquid, characterized by a low boiling point and a potent odor. Its wide usage in scientific research includes the synthesis of polymers, substances used in agriculture, and more. It′s also used to create organic and inorganic compounds, including dyes, pigments, and catalysts. As a highly reactive compound, 1,4-Diisocyanatobutane readily undergoes a multitude of reactions. It can react with water to form a hydroxy-terminated polyurethane, and with amines to create polyureas. Additionally, it can react with alcohols and phenols, as well as with aldehydes, ketones, and carboxylic acids to form polyurethanes.


1,4-Diisocyanatobutane (CAS 4538-37-8) References

  1. Fabrication of biodegradable elastomeric scaffolds with sub-micron morphologies.  |  Stankus, JJ., et al. 2004. J Biomed Mater Res A. 70: 603-14. PMID: 15307165
  2. Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications.  |  Guan, J., et al. 2005. Biomaterials. 26: 3961-71. PMID: 15626443
  3. Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrix.  |  Stankus, JJ., et al. 2006. Biomaterials. 27: 735-44. PMID: 16095685
  4. Development of composite porous scaffolds based on collagen and biodegradable poly(ester urethane)urea.  |  Guan, J., et al. 2006. Cell Transplant. 15 Suppl 1: S17-27. PMID: 16826792
  5. Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization.  |  Stankus, JJ., et al. 2007. Biomaterials. 28: 2738-46. PMID: 17337048
  6. Synthesis and characterization of segmented poly(esterurethane urea) elastomers for bone tissue engineering.  |  Kavlock, KD., et al. 2007. Acta Biomater. 3: 475-84. PMID: 17418651
  7. Tailoring the degradation kinetics of poly(ester carbonate urethane)urea thermoplastic elastomers for tissue engineering scaffolds.  |  Hong, Y., et al. 2010. Biomaterials. 31: 4249-58. PMID: 20188411
  8. Characterization of the complete fiber network topology of planar fibrous tissues and scaffolds.  |  D'Amore, A., et al. 2010. Biomaterials. 31: 5345-54. PMID: 20398930
  9. Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold.  |  Nelson, DM., et al. 2011. Pharm Res. 28: 1282-93. PMID: 21347565
  10. Degradable segmented polyurethane elastomers for bone tissue engineering: effect of polycaprolactone content.  |  Kavlock, KD., et al. 2013. J Biomater Sci Polym Ed. 24: 77-93. PMID: 22304961
  11. Synthesis, characterization, and paclitaxel release from a biodegradable, elastomeric, poly(ester urethane)urea bearing phosphorylcholine groups for reduced thrombogenicity.  |  Hong, Y., et al. 2012. Biomacromolecules. 13: 3686-94. PMID: 23035885
  12. Gelatin-modified polyurethanes for soft tissue scaffold.  |  Kucińska-Lipka, J., et al. 2013. ScientificWorldJournal. 2013: 450132. PMID: 24363617
  13. Novel Poly(3-hydroxybutyrate-g-vinyl alcohol) Polyurethane Scaffold for Tissue Engineering.  |  Reyes, AP., et al. 2016. Sci Rep. 6: 31140. PMID: 27502732

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,4-Diisocyanatobutane, 1 g

sc-253989
1 g
$129.00

1,4-Diisocyanatobutane, 5 g

sc-253989A
5 g
$490.00

1,4-Diisocyanatobutane, 50 g

sc-253989B
50 g
$983.00

1,4-Diisocyanatobutane, 500 g

sc-253989C
500 g
$3779.00