Date published: 2025-10-2

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1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide (CAS 769-49-3)

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Alternate Names:
1-Methyl-4-pyridone-3-carboxamide; 1-Methyl-4-pyridone-5-carboxamide
Application:
1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide is 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide has been shown to be one of the potential novel biomarkers of peroxisome proliferation in the rat.
CAS Number:
769-49-3
Molecular Weight:
152.15
Molecular Formula:
C7H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide is a metabolite of nicotinic acid and a uremic toxin. It may act to be one of the potential novel biomarkers of peroxisome proliferation in the rat. This compound also alters energy metabolism by inhibiting mitochondrial ATP production and glycolysis.


1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide (CAS 769-49-3) References

  1. Plant breeding involving genetic engineering does not result in unacceptable unintended effects in rice relative to conventional cross-breeding.  |  Liu, Q., et al. 2020. Plant J. 103: 2236-2249. PMID: 32593184
  2. Genome-wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci.  |  Wang, Z., et al. 2021. Clin Transl Med. 11: e290. PMID: 33634981
  3. A Method to Monitor the NAD+ Metabolome-From Mechanistic to Clinical Applications.  |  Giner, MP., et al. 2021. Int J Mol Sci. 22: PMID: 34638936
  4. The Antidepressant Effect of Deoiled Sunflower Seeds on Chronic Unpredictable Mild Stress in Mice Through Regulation of Microbiota-Gut-Brain Axis.  |  Lu, X., et al. 2022. Front Nutr. 9: 908297. PMID: 35859751
  5. Altered Urinary Metabolomics in Hereditary Angioedema.  |  Wang, X. and Zhi, Y. 2022. Metabolites. 12: PMID: 36422280

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide, 10 mg

sc-498106
10 mg
$388.00