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1,4-Benzodioxan-6-amine (CAS 22013-33-8)

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Alternate Names:
6-Amino-1,4-benzodioxan
CAS Number:
22013-33-8
Molecular Weight:
151.16
Molecular Formula:
C8H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,4-Benzodioxan-6-amine is a compound that functions as a building block in organic synthesis. It serves as a key intermediate in the production of various chemical compounds, including agrochemicals, and materials. 1,4-Benzodioxan-6-Amine undergoes specific chemical reactions, such as nucleophilic substitution and reductive amination, to form new molecular structures with desired properties. At the molecular level, 1,4-Benzodioxan-6-amine participates in bond formation and modification processes, contributing to the creation of diverse chemical entities. 1,4-Benzodioxan-6-Amine′s role in chemical synthesis enables the creation of new materials and compounds for further investigation and potential utilization in experimental applications.


1,4-Benzodioxan-6-amine (CAS 22013-33-8) References

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  2. Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90 inhibitors and anticancer agents.  |  Malayeri, SO., et al. 2017. Bioorg Med Chem. 25: 1294-1302. PMID: 28073608
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  5. Palladium-catalyzed selective synthesis of 3,4-dihydroquinazolines from electron-rich arylamines, electron-poor arylamines and glyoxalates.  |  Wu, C., et al. 2018. Org Biomol Chem. 16: 5050-5054. PMID: 29956708
  6. Room temperature N-heterocyclic carbene manganese catalyzed selective N-alkylation of anilines with alcohols.  |  Huang, M., et al. 2019. Chem Commun (Camb). 55: 6213-6216. PMID: 31073582
  7. 2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides.  |  Rabea, SM., et al. 2019. ACS Med Chem Lett. 10: 726-731. PMID: 31097990
  8. Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells.  |  Coles, GL., et al. 2020. Cancer Cell. 38: 129-143.e7. PMID: 32531271
  9. Nucleophilic substitution reactions of monofunctional nucleophilic reagents with cyclotriphosphazenes containing 2,2-dioxybiphenyl units.  |  Tanriverdİ EÇİk, E., et al. 2020. Turk J Chem. 44: 87-98. PMID: 33488145
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  11. Silver-Catalyzed One-Pot Three-Component Synthesis of α-Aminonitriles and Biologically Relevant α-Amino-phosphonates.  |  Pandey, VK., et al. 2022. Chem Asian J. 17: e202200703. PMID: 35950231
  12. Investigation of nucleophilic substitution pathway for the reactions of 1,4-benzodioxan-6-amine with chlorocyclophosphazenes  |  H İbişoğlu, S Beşli, F Yuksel, İ Ün, A Kılıç. 2014. Inorganica Chimica Acta. Volume 409, Part B: 216-226.
  13. N-(4-bromobenzylidene)-2, 3-dihydrobenzo [b][1, 4] dioxin-6-amine: Synthesis, crystal structure, docking and in-vitro inhibition of PLA2  |  Hema, M. K., ArunRenganathan, R. R., Nanjundaswamy, S., Karthik, C. S., Mohammed, Y. H. I., Alghamdi, S.,.. & Mallu, P. 2020. Journal of Molecular Structure. 1218: 128441.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,4-Benzodioxan-6-amine, 10 g

sc-223010
10 g
$52.00

1,4-Benzodioxan-6-amine, 50 g

sc-223010A
50 g
$169.00