Molecular structure of 1,3-PB-ITU dihydrobromide
1,3-PB-ITU dihydrobromide
Application:
1,3-PB-ITU dihydrobromide is a selective inhibitor for NOS2
Molecular Weight:
444.25
Molecular Formula:
C12H18N4S2•2HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
1,3-PB-ITU dihydrobromide is a potent and selective inhibitor of NOS2 (iNOS), with Ki = 47nM for NOS2 and Ki = 9.0μM for NOS3.
1,3-PB-ITU dihydrobromide References
- Real-time electrochemical detection of extracellular nitric oxide in tobacco cells exposed to cryptogein, an elicitor of defence responses. | Besson-Bard, A., et al. 2008. J Exp Bot. 59: 3407-14. PMID: 18653691
- Asymmetric dimethylarginine positively modulates calcium-sensing receptor signalling to promote lipid accumulation. | Dowsett, L., et al. 2023. Cell Signal. 107: 110676. PMID: 37028778
- Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. | Garvey, EP., et al. 1994. J Biol Chem. 269: 26669-76. PMID: 7523409
Inhibitor of:
Enzyme, NOS1, and NOS2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,3-PB-ITU dihydrobromide, 10 mg | sc-220549 | 10 mg | $20.00 |