Molecular structure of 1,3-Dimethyluracil, CAS Number: 874-14-6
1,3-Dimethyluracil (CAS 874-14-6)
CAS Number:
874-14-6
Molecular Weight:
140.14
Molecular Formula:
C6H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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1,3-Dimethyluracil, referred to as DMU, is a synthetic molecule that has gained significant traction in scientific research due to its versatility. In scientific research, 1,3-Dimethyluracil has been widely employed in numerous applications. In vitro investigations have employed 1,3-Dimethyluracil to study enzyme inhibition, drug metabolism, and interactions with drug targets. Moreover, the compound has been instrumental in unraveling cell metabolism, cell signaling, and gene expression mechanisms. The mode of action of 1,3-Dimethyluracil is believed to involve competitive inhibition of specific enzymes, such as cytochrome P450 enzymes.
1,3-Dimethyluracil (CAS 874-14-6) References
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- (1,3-Dimethyluracil-5-yl)mercury(II): Preparative, Structural, and NMR Spectroscopic Studies of an Analog of CH(3)Hg(II). | Zamora, F., et al. 1996. Inorg Chem. 35: 4858-4864. PMID: 11666685
- The acidity of uracil and uracil analogs in the gas phase: four surprisingly acidic sites and biological implications. | Kurinovich, MA. and Lee, JK. 2002. J Am Soc Mass Spectrom. 13: 985-95. PMID: 12216739
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- Synthesis of pyrazolo[1,5-alpha]pyrimidinone regioisomers. | Gavrin, LK., et al. 2007. J Org Chem. 72: 1043-6. PMID: 17253833
- Radical formation in pyrimidines. IV. 1,3-dimethyluracil, a non-hydrogen-bonding crystal. | Flossmann, W. and Zehner, H. 1979. Int J Radiat Biol Relat Stud Phys Chem Med. 36: 249-60. PMID: 227803
- Scalar relaxation of the second kind: a potential source of information on the dynamics of molecular movements. 1. Investigation of solution reorientation of N-methylpyridone and 1,3-dimethyluracil using measurements of longitudinal relaxation rates in the rotating frame. | Gryff-Keller, A. and Kubica, D. 2012. J Phys Chem A. 116: 9632-8. PMID: 22971246
- From 2,4-dimethoxypyrimidine to 1,3-dimethyluracil: isomerization and hydrogenation enthalpies and noncovalent interactions. | Galvão, TL., et al. 2014. J Phys Chem A. 118: 4816-23. PMID: 24933026
- Electroreductive Intermolecular Coupling of Uracils with Aromatic Ketones: Synthesis of 6-Substituted and cis-5,6-Disubstituted 5,6-Dihydro-1,3-dimethyluracils and Their Transformation to 6-Substituted 1,3-Dimethyluracils, trans-5,6-Disubstituted 5,6-Dihydro-1,3-dimethyluracils, and 4,5,5-Trisubstituted 3-Methyloxazolizin-2-ones. | Kise, N., et al. 2016. J Org Chem. 81: 5101-19. PMID: 27172090
- The reactions of the hydroxymethyl radical with 1,3-dimethyluracil and 1,3-dimethylthymine. | Schuchmann, HP., et al. 1986. Int J Radiat Biol Relat Stud Phys Chem Med. 50: 1051-68. PMID: 3025117
- The SO4(.-)-induced chain reaction of 1,3-dimethyluracil with peroxodisulphate. | Schuchmann, HP., et al. 1987. Int J Radiat Biol Relat Stud Phys Chem Med. 51: 441-53. PMID: 3494697
- [UV-dimerization of 1,3-dimethyluracil in ice-matrix]. | Fahr, E., et al. 1972. Z Naturforsch B Anorg Chem Org Chem Biochem Biophys Biol. 27: 1475-80. PMID: 4143989
- The photochemical reactions of 1,3-dimethyluracil with 1-aminopropane and poly-L-lysine. | Gorelic, LS., et al. 1972. Photochem Photobiol. 16: 469-80. PMID: 4643091
- Photochemistry of 2,4-diketopyrimidines. Photodimerization, photohydration and stacking association of 1,3-dimethyluracil in aqueous solution. | Stepień, E., et al. 1973. Acta Biochim Pol. 20: 313-24. PMID: 4749669
- Selective photoreductions of nucleic acids and their building stones. 8. Photoreduction and dimerization of 1,3-dimethyluracil. | Kondo, Y. and Witkop, B. 1969. J Am Chem Soc. 91: 5264-70. PMID: 5802927
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,3-Dimethyluracil, 5 g | sc-253983 | 5 g | $139.00 |