Date published: 2025-9-26

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1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (CAS 7226-23-5)

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Alternate Names:
1,3-Dimethyl-2-oxohexahydropyrimidine, N,N′-Dimethylpropylene urea, DMPU
CAS Number:
7226-23-5
Purity:
≥99%
Molecular Weight:
128.17
Molecular Formula:
C6H12N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone is a notable chemical compound primarily recognized for its utility in the realm of organic synthesis and catalysis. This compound is distinguished by its structural basis—a pyrimidine ring, which is a six-membered heterocyclic ring containing nitrogen atoms at the first and third positions. The structure is further augmented by the addition of methyl groups and a unique saturation in the tetrahydro modification, which bestows upon it distinctive chemical properties. In research contexts, this chemical has been extensively employed as both a solvent and a reagent. Its effectiveness in stabilizing reaction intermediates enables it to facilitate a diverse range of chemical transformations. Moreover, due to its functional groups, including ketone and amine, it serves as an excellent ligand and catalyst in various organic reactions. These properties have rendered it a valuable tool in studies involving nucleophilic substitution reactions, ring-opening polymerizations, and as a precursor in synthesizing more complex organic molecules. The use of 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone in these capacities significantly aids in enriching the understanding of complex reaction mechanisms and kinetics within the field of organic chemistry.


1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (CAS 7226-23-5) References

  1. Cobalt-catalyzed ortho-alkylation of secondary benzamide with alkyl chloride through directed C-H bond activation.  |  Chen, Q., et al. 2011. J Am Chem Soc. 133: 428-9. PMID: 21158468
  2. One-Step Cascade Synthesis of ortho-bay-Imidazolo-Extended Perylene Biscarboximides (OBISIM) and Their Application as Broad-Spectrum Fluorescent Dyes.  |  Langhals, H., et al. 2024. J Org Chem. 89: 2138-2154. PMID: 38237148

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 25 g

sc-253980
25 g
$23.00

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 100 g

sc-253980A
100 g
$40.00

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 1 kg

sc-253980B
1 kg
$280.00

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 2.5 kg

sc-253980C
2.5 kg
$660.00

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 5 kg

sc-253980D
5 kg
$920.00

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone, 10 kg

sc-253980E
10 kg
$1740.00