Date published: 2026-6-2

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1,3-Dichlorotetrafluoroacetone (CAS 127-21-9)

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CAS Number:
127-21-9
Molecular Weight:
198.93
Molecular Formula:
C3Cl2F4O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Dichlorotetrafluoroacetone is utilized as a reagent in organic synthesis research due to its properties as a halogenated building block. Researchers employ this compound in the synthesis of various organofluorine compounds, leveraging its reactivity to introduce fluorine atoms into target molecules, which can significantly alter their chemical and physical properties. Its use is also notable in the study of reaction mechanisms where the stability provided by the fluorine atoms is beneficial. In addition, 1,3-Dichlorotetrafluoroacetone serves as a key compound in the investigation of new synthetic pathways, particularly those aiming to improve the efficiency of fluorination reactions.


1,3-Dichlorotetrafluoroacetone (CAS 127-21-9) References

  1. Derivatization of amino acids with 1,3-dichlorotetrafluoroacetone and its use in gas chromatography.  |  Husek, P. 1974. J Chromatogr. 91: 475-81. PMID: 4833133
  2. Rapid and effective separation of thyroid hormones and iodide by thin-layer chromatography.  |  Husek, P. and Felt, V. 1976. Clin Chim Acta. 72: 195-9. PMID: 975575

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-Dichlorotetrafluoroacetone, 1 g

sc-281233A
1 g
$31.00

1,3-Dichlorotetrafluoroacetone, 5 g

sc-281233
5 g
$79.00

1,3-Dichlorotetrafluoroacetone, 25 g

sc-281233B
25 g
$307.00

1,3-Dichlorotetrafluoroacetone, 100 g

sc-281233C
100 g
$1103.00