Molecular structure of 1,3-dichloropropan-2-ol, CAS Number: 96-23-1
1,3-dichloropropan-2-ol (CAS 96-23-1)
CAS Number:
96-23-1
Molecular Weight:
128.99
Molecular Formula:
C3H6Cl2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,3-dichloropropan-2-ol is a colorless or amber-colored liquid soluble in water, ethanol, and ether. It is a prevalent intermediate chemical used to synthesize other substances like glycerol and epoxides. In scientific endeavors, 1,3-dichloropropan-2-ol finds extensive applications, notably in the creation of herbicides, pesticides, and fungicides. This compound acts as a chlorinating agent and has been used as a reactive solution in glycerol analysis. It′s instrumental in determining the chloride content present in liquid samples. When 1,3-dichloropropan-2-ol interacts with glycerin, it forms glycerol dichlorohydrin, which can then be analyzed using specific analytical techniques.
1,3-dichloropropan-2-ol (CAS 96-23-1) References
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- 1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells. | Park, SY., et al. 2010. Biotechnol Lett. 32: 45-51. PMID: 19731046
- Toxicology, occurrence and risk characterisation of the chloropropanols in food: 2-monochloro-1,3-propanediol, 1,3-dichloro-2-propanol and 2,3-dichloro-1-propanol. | Andres, S., et al. 2013. Food Chem Toxicol. 58: 467-78. PMID: 23712097
- 1,3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathway. | Lu, J., et al. 2014. Food Chem Toxicol. 64: 403-9. PMID: 24333398
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- Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway. | Lu, J., et al. 2018. Life Sci. 195: 19-24. PMID: 29305303
- Epigallocatechin-3-gallate protects against 1,3-dichloro-2-propanol-induced lipid accumulation in C57BL/6J mice. | Lu, J., et al. 2018. Life Sci. 209: 324-331. PMID: 30092300
- 1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells. | Cheng, B., et al. 2018. Food Chem Toxicol. 122: 143-150. PMID: 30316840
- Caffeic acid abrogates 1,3-dichloro-2-propanol-induced hepatotoxicity by upregulating nuclear erythroid-related factor 2 and downregulating nuclear factor-kappa B. | Ajiboye, TO., et al. 2019. Hum Exp Toxicol. 38: 1092-1101. PMID: 31142131
- 1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells. | Lu, J., et al. 2021. Toxicology. 454: 152716. PMID: 33581215
- 1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice. | Fan, Y., et al. 2021. Food Chem Toxicol. 157: 112578. PMID: 34560177
- Diallyl disulfide prevents 1,3-dichloro-2-propanol-induced hepatotoxicity through mitogen-activated protein kinases signaling. | Kim, JW., et al. 2022. Food Chem Toxicol. 160: 112814. PMID: 34999178
- 1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes. | Guan, S., et al. 2022. Environ Toxicol. 37: 2515-2528. PMID: 35870111
- 1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway. | Fan, Y., et al. 2022. J Agric Food Chem. 70: 10847-10857. PMID: 36000575
- 1,3-dichloro-2-propanol caused lipid droplets accumulation by suppressing neutral lipases via BMAL1 in hepatocytes. | Fan, Y., et al. 2023. Food Chem Toxicol. 174: 113670. PMID: 36805544
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,3-dichloropropan-2-ol, 1 g | sc-334226 | 1 g | $60.00 | |||
1,3-dichloropropan-2-ol, 5 g | sc-334226A | 5 g | $273.00 |