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1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene (CAS 688348-37-0)

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Alternate Names:
CAY10464
Application:
1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene is a potent, selective antagonist of the aryl hydrocarbon receptor
CAS Number:
688348-37-0
Molecular Weight:
279.16
Molecular Formula:
C15H12Cl2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene is useful for the molecular biology and biochemistry research, particularly in the study of cellular pathways and protein function. 1,3-Dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene interacts with precise molecular targets, facilitating the modulation of their biological activity and altering downstream cellular processes. Its role in research is based on its ability to bind selectively to these targets, thereby influencing cellular signaling pathways and gene expression profiles. This selective binding disrupts specific molecular interactions or biochemical reactions, making it a useful agent for dissecting the complex mechanisms governing cellular functions.


1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene (CAS 688348-37-0) References

  1. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals.  |  Denison, MS. and Nagy, SR. 2003. Annu Rev Pharmacol Toxicol. 43: 309-34. PMID: 12540743
  2. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators.  |  de Medina, P., et al. 2005. J Med Chem. 48: 287-91. PMID: 15634023
  3. Resveratrol Analogs with Antioxidant Activity Inhibit Intestinal Epithelial Cancer Caco-2 Cell Growth by Modulating Arachidonic Acid Cascade.  |  Storniolo, CE. and Moreno, JJ. 2019. J Agric Food Chem. 67: 819-828. PMID: 30575383
  4. Tris (2,3-Dibromopropyl) Isocyanurate (TDBP-TAZTO or TBC) Shows Different Toxicity Depending on the Degree of Differentiation of the Human Neuroblastoma (SH-SY5Y) Cell Line.  |  Szychowski, KA., et al. 2021. Neurotox Res. 39: 1575-1588. PMID: 34342853
  5. Crosstalk between the aryl hydrocarbon receptor (AhR) and the peroxisome proliferator-activated receptor gamma (PPARγ) as a key factor in the metabolism of silver nanoparticles in neuroblastoma (SH-SY5Y) cells in vitro.  |  Skóra, B., et al. 2023. Toxicol Appl Pharmacol. 458: 116339. PMID: 36473513

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene, 10 mg

sc-220545
10 mg
$22.00

1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene, 25 mg

sc-220545A
25 mg
$51.00