Date published: 2026-1-9

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1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (CAS 69304-37-6)

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Alternate Names:
TIPDSiCl2
CAS Number:
69304-37-6
Molecular Weight:
315.43
Molecular Formula:
C12H28Cl2OSi2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane exhibits miscibility with numerous organic solvents while remaining insoluble in water. This versatile compound finds wide-ranging applications in scientific research, encompassing the synthesis of organic and inorganic compounds, catalyst development, and the exploration of molecular interactions. It serves as a valuable solvent for chromatography and a reagent in polymer synthesis. Additionally, it acts as a stabilizer for polymers and a surfactant in emulsions.


1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (CAS 69304-37-6) References

  1. Reductive olefination of aldehydes via chromium Brook rearrangement.  |  Baati, R., et al. 2006. Org Lett. 8: 2949-51. PMID: 16805524
  2. The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates.  |  Santner, T., et al. 2012. Bioorg Med Chem. 20: 2416-8. PMID: 22364745
  3. Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors.  |  Zhou, L., et al. 2013. Bioorg Med Chem Lett. 23: 3385-8. PMID: 23623492
  4. Efficient access to N-trifluoroacetylated 2'-amino-2'-deoxyadenosine phosphoramidite for RNA solid-phase synthesis.  |  Falschlunger, C. and Micura, R. 2019. Monatsh Chem. 150: 795-800. PMID: 31178603
  5. Chemo-Enzymatic Modification of the 5' Cap Maintains Translation and Increases Immunogenic Properties of mRNA.  |  van Dülmen, M., et al. 2021. Angew Chem Int Ed Engl. 60: 13280-13286. PMID: 33751748
  6. Targeted Synthesis of 3,3'-, 3,4'- and 3,6'-Phenylpropanoid Sucrose Esters.  |  Kathy, WPW., et al. 2022. Molecules. 27: PMID: 35056850

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 1 g

sc-251584
1 g
$58.00