Date published: 2025-10-19

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1,3-Diaminopropane (CAS 109-76-2)

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Alternate Names:
1,3-Propanediamine
Application:
1,3-Diaminopropane is a common synthesis reagent
CAS Number:
109-76-2
Purity:
≥98%
Molecular Weight:
74.12
Molecular Formula:
C3H10N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Diaminopropane is an organic compound. Exhibiting a colorless appearance, it presents itself as a flammable liquid characterized by a potent ammonia-like scent. The biochemical and physiological effects of 1,3-diaminopropane have been thoroughly explored in diverse scientific research endeavors. 1,3-Diaminopropane exerts its effects through the modulation of various enzymes and proteins. Notably, it acts as an inhibitor of nitric oxide synthase, a pivotal enzyme responsible for nitric oxide production.


1,3-Diaminopropane (CAS 109-76-2) References

  1. The inducers 1,3-diaminopropane and spermidine produce a drastic increase in the expression of the penicillin biosynthetic genes for prolonged time, mediated by the laeA regulator.  |  Martín, J., et al. 2012. Fungal Genet Biol. 49: 1004-13. PMID: 23089625
  2. The inducers 1,3-diaminopropane and spermidine cause the reprogramming of metabolism in Penicillium chrysogenum, leading to multiple vesicles and penicillin overproduction.  |  García-Estrada, C., et al. 2013. J Proteomics. 85: 129-59. PMID: 23639845
  3. Copper-catalyzed aerobic synthesis of 2-arylpyridines from acetophenones and 1,3-diaminopropane.  |  Xi, LY., et al. 2014. Org Lett. 16: 5269-71. PMID: 25285847
  4. Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine.  |  Chae, TU., et al. 2015. Sci Rep. 5: 13040. PMID: 26260768
  5. Dissociation of cephamycin C and clavulanic acid biosynthesis by 1,3-diaminopropane in Streptomyces clavuligerus.  |  Leite, CA., et al. 2016. FEMS Microbiol Lett. 363: fnv215. PMID: 26564965
  6. The Essential Role of Spermidine in Growth of Agrobacterium tumefaciens Is Determined by the 1,3-Diaminopropane Moiety.  |  Kim, SH., et al. 2016. ACS Chem Biol. 11: 491-9. PMID: 26682642
  7. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs.  |  Liu, R., et al. 2017. Oncotarget. 8: 88575-88585. PMID: 29179458
  8. Modification of multi-walled carbon nanotubes by 1,3-diaminopropane to increase CO2 adsorption capacity.  |  Rahimi, K., et al. 2019. J Environ Manage. 242: 81-89. PMID: 31028954
  9. Inhibitory effects of 1,3-diaminopropane on the biofilm formation of Pseudomonas aeruginosa via interaction with quorum sensing system.  |  She, P., et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 46: 942-948. PMID: 34707003
  10. Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine.  |  Mattioli, R., et al. 2022. Plant Physiol Biochem. 170: 123-132. PMID: 34871830
  11. Spermidine and 1,3-Diaminopropane Have Opposite Effects on the Final Stage of Cephalosporin C Biosynthesis in High-Yielding Acremonium chrysogenum Strain.  |  Zhgun, AA. and Eldarov, MA. 2022. Int J Mol Sci. 23: PMID: 36498951
  12. Benzothiazole-based novel fluorescence probe sensing 1, 3-diaminopropane.  |  Mishra, S. and Kumar Singh, A. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 299: 122799. PMID: 37187148
  13. Polyamine, 1,3-diaminopropane, regulates defence responses on growth, gas exchange, PSII photochemistry and antioxidant system in wheat under arsenic toxicity.  |  Gulenturk, C., et al. 2023. Plant Physiol Biochem. 201: 107886. PMID: 37451004
  14. Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver.  |  Seely, JE. and Pegg, AE. 1983. Biochem J. 216: 701-7. PMID: 6667263
  15. Polyamines in Acanthamoeba castellanii: presence of an unusually high, osmotically sensitive pool of 1,3-diaminopropane.  |  Poulin, R., et al. 1984. Biochem Biophys Res Commun. 122: 388-93. PMID: 6743339

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-Diaminopropane, 25 g

sc-255920
25 g
$28.00

1,3-Diaminopropane, 500 g

sc-255920A
500 g
$69.00

1,3-Diaminopropane, 1 kg

sc-255920B
1 kg
$102.00

1,3-Diaminopropane, 2.5 kg

sc-255920C
2.5 kg
$204.00