Molecular structure of 1,3-Diacetylbenzene, CAS Number: 6781-42-6
1,3-Diacetylbenzene (CAS 6781-42-6)
Alternate Names:
1-(3-acetylphenyl)ethanone; M-acetylacetophenone
CAS Number:
6781-42-6
Purity:
≥97%
Molecular Weight:
162.19
Molecular Formula:
C10H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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1,3-Diacetylbenzene, also referred to as 1,3-Benzenedicarboxylic acid, is an organic compound of cyclic nature that finds extensive use in various scientific applications. This colorless, crystalline solid emits a faint odor and exhibits high solubility in water. It serves as a starting material for synthesizing a diverse range of organic compounds. Further, 1,3-Diacetylbenzene has contributed to unraveling the structure and reactivity of organic compounds. Although the precise mechanism of action of 1,3-diacetylbenzene remains incompletely understood, it is believed to engage with the active sites of enzymes and other biological molecules, thereby inducing alterations in their structure and functionality.
1,3-Diacetylbenzene (CAS 6781-42-6) References
- Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy. | Kim, MS., et al. 2002. Toxicol Appl Pharmacol. 183: 55-65. PMID: 12217642
- Axonopathy-inducing 1,2-diacetylbenzene forms adducts with motor and cytoskeletal proteins required for axonal transport. | Sabri, MI., et al. 2007. Neurochem Res. 32: 2152-9. PMID: 17577667
- Toxic neurofilamentous axonopathies -- accumulation of neurofilaments and axonal degeneration. | Llorens, J. 2013. J Intern Med. 273: 478-89. PMID: 23331301
- Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H..O hydrogen bonds between the components. | Bosch, E. 2016. Acta Crystallogr C Struct Chem. 72: 748-752. PMID: 27703122
- Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines. | Tan, WW., et al. 2017. Angew Chem Int Ed Engl. 56: 8240-8244. PMID: 28524343
- Practical Synthesis of Chalcone Derivatives and Their Biological Activities. | Jung, JC., et al. 2017. Molecules. 22: PMID: 29104222
- 1,2-Diacetylbenzene impaired hippocampal memory by activating proinflammatory cytokines and upregulating the prolactin pathway: An in vivo and in vitro study. | Nguyen, HD., et al. 2022. Int Immunopharmacol. 108: 108901. PMID: 35729834
- The biosynthesis of trypanothione and N1-glutathionylspermidine in Crithidia fasciculata. | Fairlamb, AH., et al. 1986. Mol Biochem Parasitol. 21: 247-57. PMID: 3807945
- Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling. | Artico, M., et al. 1998. J Med Chem. 41: 3948-60. PMID: 9767632
- Convenient synthesis of new binucleating ligands derived from 1,3-diacetylbenzene. Possible precursors for oligomeric organometallic materials | Dominique Matt, Alain Van Dorsselaer. 1991. Polyhedron. 10: 1521-1526.
- Orthomanganated arenes in synthesis VIII. Mono- and dicyclomanganation of diacetyl benzenes | Nicholas P. Robinson, Lyndsay Main, Brian K. Nicholson. 1992. Journal of Organometallic Chemistry. 430: 79-86.
- Synthesis of chiral phosphine ligands with aromatic backbones and their applications in asymmetric catalysis | James M. Longmire, Xumu Zhang ∗. 1997. Tetrahedron Letters. 38: 1725-1728.
- Synthesis of new bis(2-[1,8]naphthyridinyl) bridging ligands with multidentate binding sites | Antonio Fernández-Mato, Gerardo Blanco, José M. Quintela, Carlos Peinador. 2008. Tetrahedron. 64: 3446-3456.
- Comparative vibrational spectroscopic study of 1,3-diacetylbenzene and 2,6-diacetylpyridine aided with density functional calculation | Pinaky Sett a, Subrato Chattopadhyay b, Prabal Kumar Mallick c. 2009. Vibrational Spectroscopy. 49: 84-95.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,3-Diacetylbenzene, 10 g | sc-237714 | 10 g | $125.00 | |||
1,3-Diacetylbenzene, 25 g | sc-237714A | 25 g | $210.00 | |||
1,3-Diacetylbenzene, 50 g | sc-237714B | 50 g | $325.00 | |||
1,3-Diacetylbenzene, 100 g | sc-237714C | 100 g | $590.00 | |||
1,3-Diacetylbenzene, 250 g | sc-237714D | 250 g | $975.00 |