1,3-Di-p-tolylcarbodiimide (CAS 726-42-1)
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1,3-Di-p-tolylcarbodiimide is a dynamic reagent employed in organic synthesis, most notably in the synthesis of peptides. As a bifunctional carbodiimide, it′s utilized to establish amide bonds between carboxylic acids and amines. The use of 1,3-Di-p-tolylcarbodiimide is prevalent in peptide synthesis and various lab experiments, making it useful in numerous scientific research endeavors. It serves as a coupling reagent in the synthesis of peptides and proteins and plays a role in the creation of nucleic acids, polymers, and carbohydrates. The functionality of 1,3-Di-p-tolylcarbodiimide hinges on the formation of a stable imide bond between the carboxylic acid and the amine. This reaction is catalyzed by the presence of a base, such as pyridine or triethylamine. Notably, this reaction is reversible, allowing the imide bond to be broken by hydrolysis.
1,3-Di-p-tolylcarbodiimide (CAS 726-42-1) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,3-Di-p-tolylcarbodiimide, 100 mg | sc-222942 | 100 mg | $455.00 | |||
1,3-Di-p-tolylcarbodiimide, 250 mg | sc-222942A | 250 mg | $1938.00 |