Date published: 2026-2-9

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1,3-Bis(trimethylsilyl)urea (CAS 18297-63-7)

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Alternate Names:
N,N′-Bis(trimethylsilyl)urea; BSU
CAS Number:
18297-63-7
Molecular Weight:
204.42
Molecular Formula:
C7H20N2OSi2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3-Bis(trimethylsilyl)urea is a white crystalline solid, highly soluble in multiple organic solvents. This compound is frequently used as a reagent in diverse scientific investigations, notably for its capacity to aid peptide sequencing, finding substantial application in proteomics. 1,3-Bis(trimethylsilyl)urea, being a derivative of flavonoid, attaches to the genome′s DNA binding proteins, disrupting DNA replication and transcription by blocking the binding of RNA polymerase to the DNA template.


1,3-Bis(trimethylsilyl)urea (CAS 18297-63-7) References

  1. Action of propranolol on mitochondrial functions--effects on energized ion fluxes in the presence of valinomycin.  |  Järvisalo, J. and Saris, NE. 1975. Biochem Pharmacol. 24: 1701-5. PMID: 13

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3-Bis(trimethylsilyl)urea, 50 g

sc-237710
50 g
$47.00