Date published: 2026-4-5

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1,3,9-Trimethylxanthine (CAS 519-32-4)

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Alternate Names:
3,9-Dihydro-1,3,9-trimethyl-1H-purine-2,6-dione; 1,3,9-Trimethylxanthine; 9-Methyltheophylline; NSC 28332; EP Impurity C for Caffeine; Isocaffeine
Application:
1,3,9-Trimethylxanthine is an Adenosine A Receptor antagonist
CAS Number:
519-32-4
Purity:
≥97%
Molecular Weight:
194.19
Molecular Formula:
C8H10N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

1,3,9-Trimethylxanthine is an Adenosine A Receptor antagonist. 1,3,9-Trimethylxanthine may be used in studies on the binding of caffeine analogues to adenosine receptors. 1,3,9-Trimethylxanthine is an inhibitor of AChE. 1,3,9-Trimethylxanthine functions by activating specific receptors in the brain, such as adenosine, dopamine, and serotonin receptors.


1,3,9-Trimethylxanthine (CAS 519-32-4) References

  1. Dramatic differences in activity of purines metabolizing ecto-enzymes between mesenchymal stem cells isolated from human umbilical cord blood and umbilical cord tissue.  |  Roszek, K., et al. 2013. Biochem Cell Biol. 91: 519-25. PMID: 24219295
  2. Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by caffeine and related compounds.  |  Rousseau, E., et al. 1988. Arch Biochem Biophys. 267: 75-86. PMID: 2848455
  3. Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart.  |  Chapman, RA. and Miller, DJ. 1974. J Physiol. 242: 615-34. PMID: 4375181
  4. Metabolism and distribution of labeled theophylline in the pregnant rat. Impairment of theophylline metabolism by pregnancy and absence of a blood-brain barrier in the fetus.  |  Arnaud, MJ., et al. 1982. Pediatr Res. 16: 167-71. PMID: 7063271
  5. Determination of caffeine and its metabolites in urine by high-performance liquid chromatography and capillary electrophoresis.  |  Rodopoulos, N. and Norman, A. 1994. Scand J Clin Lab Invest. 54: 305-15. PMID: 7939374
  6. Inhibition of inositol trisphosphate-induced calcium release by caffeine is prevented by ATP.  |  Missiaen, L., et al. 1994. Biochem J. 300 (Pt 1): 81-4. PMID: 8198556
  7. Elimination of theobromine metabolites in healthy adults.  |  Rodopoulos, N., et al. 1996. Scand J Clin Lab Invest. 56: 373-83. PMID: 8837245
  8. Elimination of theophylline metabolites in healthy adults.  |  Rodopoulos, N. and Norman, A. 1997. Scand J Clin Lab Invest. 57: 233-40. PMID: 9238759

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3,9-Trimethylxanthine, 100 mg

sc-216142
100 mg
$317.00

1,3,9-Trimethylxanthine, 500 mg

sc-216142A
500 mg
$525.00