Date published: 2026-5-8

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1,3,6,8-Tetrabromopyrene (CAS 128-63-2)

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CAS Number:
128-63-2
Molecular Weight:
517.84
Molecular Formula:
C16H6Br4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,3,6,8-Tetrabromopyrene is a chemical compound that functions as a potent halogenated aromatic hydrocarbon in experimental applications. It acts as a highly reactive compound, capable of forming covalent bonds with cellular macromolecules, particularly DNA and proteins. 1,3,6,8-Tetrabromopyrene′s mode of action involves its ability to induce genotoxicity and mutagenicity by forming DNA adducts and causing DNA damage. 1,3,6,8-Tetrabromopyrene may disrupt cellular signaling pathways and interfere with normal cellular processes, leading to potential cytotoxic effects. Its reactivity and ability to modify cellular components makes use for studying the mechanisms of chemical-induced toxicity and carcinogenesis in experimental models. In development, 1,3,6,8-Tetrabromopyrene is utilized to investigate the molecular pathways involved in chemical-induced toxicity and to assess the potential risks associated with exposure to halogenated aromatic hydrocarbons.


1,3,6,8-Tetrabromopyrene (CAS 128-63-2) References

  1. Steric inhibition of pi-stacking: 1,3,6,8-tetraarylpyrenes as efficient blue emitters in organic light emitting diodes (OLEDs).  |  Moorthy, JN., et al. 2007. Org Lett. 9: 5215-8. PMID: 17988140
  2. 1,3,6,8-tetrasubstituted pyrenes: solution-processable materials for application in organic electronics.  |  Sonar, P., et al. 2010. Org Lett. 12: 3292-5. PMID: 20586440
  3. Electronic coupling between two cyclometalated ruthenium centers bridged by 1,3,6,8-tetra(2-pyridyl)pyrene (tppyr).  |  Yao, CJ., et al. 2010. Inorg Chem. 49: 8347-50. PMID: 20734995
  4. Comparing Ullmann Coupling on Noble Metal Surfaces: On-Surface Polymerization of 1,3,6,8-Tetrabromopyrene on Cu(111) and Au(111).  |  Pham, TA., et al. 2016. Chemistry. 22: 5937-44. PMID: 26879625
  5. Fluorescence-Tuned Polyhedral Oligomeric Silsesquioxane-Based Porous Polymers.  |  Wang, D., et al. 2016. Chemistry. 22: 14319-27. PMID: 27533795
  6. Effects of substituents in silyl groups on the absorption, fluorescence and structural properties of 1,3,6,8-tetrasilylpyrenes.  |  Maeda, H., et al. 2018. Photochem Photobiol Sci. 17: 781-792. PMID: 29741552
  7. Molecular Packing and Solid-State Photophysical Properties of 1,3,6,8-Tetraalkylpyrenes.  |  Iwasaki, T., et al. 2019. Chemistry. 25: 14817-14825. PMID: 31410873
  8. Pyrene-based covalent organic framework for selective enrichment of hydrophobic peptides with simultaneous proteins exclusion.  |  Irfan, A., et al. 2022. Anal Chim Acta. 1209: 339876. PMID: 35569839
  9. Synthesis, Structure, and Optical Properties of a Bis-Macrocycle Derived from a Highly Emissive 1,3,6,8-Tetra(1H-pyrrol-2-yl)pyrene.  |  Ipe, RM., et al. 2022. J Org Chem. 87: 15022-15030. PMID: 36321998
  10. Design Hybrid Porous Organic/Inorganic Polymers Containing Polyhedral Oligomeric Silsesquioxane/Pyrene/Anthracene Moieties as a High-Performance Electrode for Supercapacitor.  |  Ejaz, M., et al. 2023. Int J Mol Sci. 24: PMID: 36768824
  11. Construction and sorption properties of pyrene-based porous aromatic frameworks  |  Yan, Z., Ren, H., Ma, H., Yuan, R., Yuan, Y., Zou, X.,.. & Zhu, G. 2013. Microporous and mesoporous materials. 173: 92-98.
  12. Pyrene-connected tetraimidazolylidene complexes of iridium and rhodium. Structural features and catalytic applications  |  Gutierrez-Blanco, A., Peris, E., & Poyatos, M. 2018. Organometallics. 37(21): 4070-4076.
  13. Ultrastable carbazole-tethered conjugated microporous polymers for high-performance energy storage  |  Ahmed, M., Kotp, M. G., Mansoure, T. H., Lee, R. H., Kuo, S. W., & EL-Mahdy, A. F. 2022. Microporous and Mesoporous Materials. 333: 111766.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,3,6,8-Tetrabromopyrene, 5 g

sc-477012
5 g
$189.00