1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose (CAS 18968-05-3)

1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose is a chemically modified form of mannose, extensively utilized in the synthesis of complex glycostructures in the field of carbohydrate chemistry. The acetyl groups at positions 1, 3, 4, and 6 serve as protective groups, making the molecule stable and resistant to unwanted side reactions during synthetic procedures. This stabilization is crucial for allowing precise and controlled chemical modifications, which are essential for the stepwise construction of oligosaccharides and glycoconjugates. Researchers use this compound to study the glycosylation process, where it acts as a glycosyl donor in the presence of catalysts to form glycosidic bonds with other sugar moieties or aglycones. This ability to form targeted bonds makes it invaluable in exploring the roles of mannose-containing structures in cellular recognition and signaling processes. In research applications, this compound aids in the development of glycomimetics and the investigation of mannose receptors and their biological pathways. Furthermore, the tailored deprotection of its acetyl groups allows for the selective introduction of other functional groups, thereby enabling the synthesis of diverse and complex glycan architectures that are significant in studying carbohydrate-based interactions within biological systems.