Molecular structure of 1,2-O-Dioctadecyl-sn-glycerol, CAS Number: 82188-61-2
1,2-O-Dioctadecyl-sn-glycerol (CAS 82188-61-2)
Alternate Names:
D-α,β-Dioctadecyl-glycerol
CAS Number:
82188-61-2
Molecular Weight:
597.06
Molecular Formula:
C39H80O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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1,2-O-Dioctadecyl-sn-glycerol (DOG) is a glycerol derivative that mimics the structure of natural phospholipids and has been used as a research tool in various fields of study. It may act to interact with lipid membranes and alter their properties. It can induce membrane fusion and activate protein kinase C. 1,2-O-Dioctadecyl-sn-glycerol can also induce the release of calcium from intracellular stores, induce apoptosis, and inhibit the growth of tumor cells in vitro. Additionally, it has been used as a substrate for phospholipase C.
1,2-O-Dioctadecyl-sn-glycerol (CAS 82188-61-2) References
- Supported membranes with well-defined polymer tethers--incorporation of cell receptors. | Purrucker, O., et al. 2004. Chemphyschem. 5: 327-35. PMID: 15067869
- Increased target specificity of anti-HER2 genospheres by modification of surface charge and degree of PEGylation. | Hayes, ME., et al. 2006. Mol Pharm. 3: 726-36. PMID: 17140260
- Activation of myocardial protein kinase C by plasmalogenic diglycerides. | Ford, DA. and Gross, RW. 1990. Am J Physiol. 258: C30-6. PMID: 2154113
- Purification, cDNA-cloning and expression of human diacylglycerol kinase. | Schaap, D., et al. 1990. FEBS Lett. 275: 151-8. PMID: 2175712
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2-O-Dioctadecyl-sn-glycerol, 1 g | sc-287224 | 1 g | $265.00 | |||
1,2-O-Dioctadecyl-sn-glycerol, 5 g | sc-287224A | 5 g | $979.00 |