1-(2-Methoxyphenyl)-1-propanol (CAS 7452-01-9)
QUICK LINKS
1-(2-Methoxyphenyl)-1-propanol is a chemical compound that has garnered attention in scientific research for its diverse applications, particularly in organic synthesis and materials science. Its structural motif, comprising a methoxyphenyl group attached to a propanol backbone, renders it a versatile building block in the synthesis of various organic compounds. In research, this chemical has been investigated for its role as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and functional materials. Its mechanism of action often involves nucleophilic substitution reactions, where the methoxy group serves as a directing group, facilitating regioselective functionalization of the aromatic ring. Additionally, 1-(2-Methoxyphenyl)-1-propanol has been utilized in the synthesis of biologically active molecules, including natural products and drug candidates. Furthermore, its presence in the molecular structure of certain polymers imparts specific properties such as solubility, thermal stability, and optical activity, making it valuable in the design and fabrication of functional materials for various technological applications. Overall, ongoing research continues to explore the synthetic versatility and potential applications of 1-(2-Methoxyphenyl)-1-propanol in diverse scientific disciplines.
1-(2-Methoxyphenyl)-1-propanol (CAS 7452-01-9) References
- An l-proline-based β-amino tertiary thiol: synthesis and use as a catalyst in the enantioselective addition of diethylzinc to aldehydes[J]. | Gibson C L. 1999. Tetrahedron: Asymmetry,., 10(8).: 1551-1561.
- Synthesis of 3 or 3, 3′-substituted BINOL ligands and their application in the asymmetric addition of diethylzinc to aromatic aldehydes[J]. | Guo Q S, Liu B, Lu Y N,. 2005,. Tetrahedron: Asymmetry,. 16(22):: 3667-3671.
- Catalytic enantioselective addition of diethylzinc to aldehydes using aziridine based chiral ligands[J]. | Bulut A, Aslan A, Izgü E Ç. 2007. Tetrahedron: Asymmetry,., 18(8):: 1013-1016.
- Tailoring the ligand structure to the reagent in the mandelamide-Ti (IV) catalyzed enantioselective addition of dimethyl-and diethylzinc to aldehydes[J]. | Blay G, Fernández I, Hernández-Olmos V. 2007,. Journal of Molecular Catalysis A: Chemical,. 276(1-2):: 235-243.
- Mild and efficient silylation of alcohols and phenols with HMDS using Bi (OTf) 3 under solvent-free condition[J]. | Kadam S T, Kim S S. 2009. Journal of Organometallic Chemistry,., 694(16):: 2562-2566.
- Fe (ClO4) 3·× H2O-Catalyzed direct C–C bond forming reactions between secondary benzylic alcohols with different types of nucleophiles[J]. | Thirupathi P, Kim S S. 2010. Tetrahedron,., 66(16):: 2995-3003.
- The synthesis of chiral amino diol tridentate ligands and their enantioselective induction during the addition of diethylzinc to aldehydes[J]. | Zhang A, Yang L, Yang N,. 2014,. Tetrahedron: Asymmetry,. 25(4):: 289-297.
- Enantioselective addition of diethylzinc to aldehydes catalyzed by (R)-1-phenylethylamine-derived 1, 4-amino alcohols[J]. | Asami M, Miyairi N, Sasahara Y. 2015. Tetrahedron,., 71(38):: 6796-6802.
- Enantioselective addition of diethylzinc to aldehydes catalyzed by o-xylylene-type chiral 1, 4-amino alcohols with an aminal structure[J]. | Asami M, Hasome A, Yachi N. 2016. Tetrahedron: Asymmetry,., 27(7-8):: 322-329.
- Preparation of several BINOL-based polymeric ligands for the enantioselective addition of triethylaluminium to aromatic aldehydes[J]. | Liu D, Ouyang K, Yang N. 2016,. Tetrahedron,. 72(7):: 1018-1023.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-(2-Methoxyphenyl)-1-propanol, 1 g | sc-222485 | 1 g | $31.00 |