1-(2-Hydroxyethyl)piperazine (CAS 103-76-4)
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1-(2-Hydroxyethyl)piperazine is a compound that functions as a versatile building block in the synthesis of various chemicals and materials. It acts as a key intermediate in the production of agrochemicals, and surfactants. Its mechanism of action involves its ability to undergo nucleophilic substitution reactions, allowing it to participate in the formation of complex molecular structures. 1-(2-Hydroxyethyl)Piperazine has reactivity with a wide range of functional groups, making it useful in the development of diverse chemical compounds. Its role in the modification of organic molecules and polymers is significant, as it contributes to the creation of new materials with tailored properties. In experimental applications, 1-(2-Hydroxyethyl)piperazine plays a role in the synthesis of compounds with potential applications in various industries, including agriculture, and materials science.
1-(2-Hydroxyethyl)piperazine (CAS 103-76-4) References
- Kinetics and mechanisms of the reactions of 3-methoxyphenyl, 3-chlorophenyl, and 4-cyanophenyl 4-nitrophenyl thionocarbonates with alicyclic amines. | Castro, EA., et al. 2001. J Org Chem. 66: 6130-5. PMID: 11529741
- The study on organic nitrates, part V. New derivatives of piperazine potential NO donors. | Korzycka, L. 2002. J Pharm Pharmacol. 54: 445-50. PMID: 11902813
- Kinetic and mechanistic investigation of the aminolysis of 3-methoxyphenyl 3-nitrophenyl thionocarbonate, 3-chlorophenyl 3-nitrophenyl thionocarbonate, and bis(3-nitrophenyl) thionocarbonate. | Castro, EA., et al. 2002. J Org Chem. 67: 4309-15. PMID: 12054968
- Complexation of copper by zwitterionic aminosulfonic (good) buffers. | Mash, HE., et al. 2003. Anal Chem. 75: 671-7. PMID: 12585500
- Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. | Lombardo, LJ., et al. 2004. J Med Chem. 47: 6658-61. PMID: 15615512
- Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin. | Grguric-Sipka, S., et al. 2009. Dalton Trans. 3334-9. PMID: 19421637
- Synthesis of piperazine functionalized magnetic sporopollenin: a new organic-inorganic hybrid material for the removal of lead(II) and arsenic(III) from aqueous solution. | Ahmad, NF., et al. 2017. Environ Sci Pollut Res Int. 24: 21846-21858. PMID: 28776296
- Synthesis of nanosized SAPO-34 with the assistance of bifunctional amine and seeds. | Wu, P., et al. 2018. Chem Commun (Camb). 54: 11160-11163. PMID: 30226517
- Substituted Piperazines as Novel Potential Radioprotective Agents. | Filipova, A., et al. 2020. Molecules. 25: PMID: 31991816
- Organocatalyst in Direct C(sp2)-H Arylation of Unactivated Arenes: [1-(2-Hydroxyethyl)-piperazine]-Catalyzed Inter-/Intra-molecular C-H Bond Activation. | Yadav, L., et al. 2020. J Org Chem. 85: 8121-8141. PMID: 32438807
- Multiobjective Evaluation of Amine-Based Absorbents for SO2 Capture Process Using the pK a Mathematical Model. | Wang, D., et al. 2022. ACS Omega. 7: 2897-2907. PMID: 35097284
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-(2-Hydroxyethyl)piperazine, 100 g | sc-222482 | 100 g | $23.00 | |||
| US: (Out of Stock: Availability March 30, 2026) | ||||||
1-(2-Hydroxyethyl)piperazine, 500 g | sc-222482A | 500 g | $133.00 | |||