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1,2-Dipalmitoyl-sn-glycerol (CAS 30334-71-5)

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Alternate Names:
(S)-1,2-Dipalmitin
Application:
1,2-Dipalmitoyl-sn-glycerol is a DAG analog and weak PKC activator
CAS Number:
30334-71-5
Purity:
≥95%
Molecular Weight:
568.91
Molecular Formula:
C35H68O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Dipalmitoyl-sn-glycerol, a chemical compound of interest in scientific research, has been extensively studied for its various mechanisms of action and applications across different fields. Investigations have focused on unraveling the functions and properties of this compound. Research has shown that 1,2-Dipalmitoyl-sn-glycerol plays a crucial role in lipid metabolism and signaling pathways. It is involved in lipid biosynthesis as a precursor for the synthesis of complex lipids, such as phospholipids and triglycerides. The compound has been utilized in studies exploring lipid homeostasis, lipid droplet formation, and lipid-related diseases. Furthermore, 1,2-Dipalmitoyl-sn-glycerol has found applications in the field of membrane biophysics. Its unique structural characteristics, including its long-chain fatty acid composition, contribute to its ability to form stable lipid bilayers. Researchers have employed this compound to investigate membrane properties, such as fluidity, permeability, and membrane-protein interactions. It has also been used as a model system to study membrane fusion, vesicle formation, and liposome-based drug delivery systems. In addition, studies have examined the role of 1,2-Dipalmitoyl-sn-glycerol in cellular processes such as cell signaling and cell membrane integrity. The compound has been investigated in the context of lipid-mediated signaling pathways, including protein kinase C (PKC) activation, intracellular calcium dynamics, and membrane receptor functions.


1,2-Dipalmitoyl-sn-glycerol (CAS 30334-71-5) References

  1. Simultaneous X-ray diffraction and calorimetric study of metastable- to-stable solid phase transformation of 1,2-dipalmitoyl-sn-glycerol.  |  Takahashi, H., et al. 1999. Biophys Chem. 77: 173-81. PMID: 10326250
  2. Amended final report on the safety assessment of glyceryl dilaurate, glyceryl diarachidate, glyceryl dibehenate, glyceryl dierucate, glyceryl dihydroxystearate, glyceryl diisopalmitate, glyceryl diisostearate, glyceryl dilinoleate, glyceryl dimyristate, glyceryl dioleate, glyceryl diricinoleate, glyceryl dipalmitate, glyceryl dipalmitoleate, glyceryl distearate, glyceryl palmitate lactate, glyceryl stearate citrate, glyceryl stearate lactate, and glyceryl stearate succinate.  |  . 2007. Int J Toxicol. 26 Suppl 3: 1-30. PMID: 18273450
  3. Acyl migration in 1,2-dipalmitoyl-sn-glycerol.  |  Kodali, DR., et al. 1990. Chem Phys Lipids. 52: 163-70. PMID: 2160332
  4. Actual ratios of triacylglycerol positional isomers consisting of saturated and highly unsaturated fatty acids in fishes and marine mammals.  |  Gotoh, N., et al. 2011. Food Chem. 127: 467-72. PMID: 23140688
  5. Antioxidants Inhibit Formation of 3-Monochloropropane-1,2-diol Esters in Model Reactions.  |  Li, C., et al. 2015. J Agric Food Chem. 63: 9850-4. PMID: 26478126
  6. Polymorphic forms of 1,2-dipalmitoyl-sn-glycerol: a combined X-ray and electron diffraction study.  |  Dorset, DL. and Pangborn, WA. 1988. Chem Phys Lipids. 48: 19-28. PMID: 3208414
  7. Activation of protein kinase C by short chain phosphatidylcholines.  |  Walker, JM. and Sando, JJ. 1988. J Biol Chem. 263: 4537-40. PMID: 3350802
  8. Surface properties of 1,2-dipalmitoyl-3-acyl-sn-glycerols.  |  Fahey, DA. and Small, DM. 1986. Biochemistry. 25: 4468-72. PMID: 3756148
  9. The phase behavior of mixed aqueous dispersions of dipalmitoyl derivatives of phosphatidylcholine and diacylglycerol.  |  López-García, F., et al. 1994. Biophys J. 66: 1991-2004. PMID: 8075333
  10. The crystal structure of 1,2-dipalmitoyl-sn-glycerol at 123 K.  |  Han, GW., et al. 1994. Chem Phys Lipids. 71: 219-28. PMID: 8076404

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Dipalmitoyl-sn-glycerol, 25 mg

sc-220517
25 mg
$31.00

1,2-Dipalmitoyl-sn-glycerol, 100 mg

sc-220517A
100 mg
$68.00