Molecular structure of 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, CAS Number: 923-61-5
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (CAS 923-61-5)
Alternate Names:
1,2-dipalmitoyl-3-phosphatidylethanolamine; Phophatidylethanolamine; PE(16:0/16:0); Dipalmitoyl phosphatidylethanolamine
Application:
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a glycerophosphonoethanolamine family member that is a useful component in model cell membranes
CAS Number:
923-61-5
Purity:
>99%
Molecular Weight:
691.96
Molecular Formula:
C37H74NO8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of glycerophosphonoethanolamine family, is a major component in biological membranes. Studies focused on interactions between 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine and cholesterol (sc-202539) show that cholesterol induces condensation of 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine monolayers in the presence of Ca2+ ions. Membranes containing a higher concentration of this compound contain more ordered lipid tails which results in a thicker membrane. Increasing 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine concentrations has also been noted to cause competitive hydrogen bonding between amine groups and phosphate/carbonyl groups or water.
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (CAS 923-61-5) References
- Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. | Leekumjorn, S. and Sum, AK. 2006. Biophys J. 90: 3951-65. PMID: 16533838
- A Langmuir film approach to elucidating interactions in lipid membranes: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine/cholesterol/metal cation systems. | Korchowiec, B., et al. 2006. Chem Phys Lipids. 144: 127-36. PMID: 17027949
- A monolayer study on phase behavior and morphology of binary mixtures of sulfatides with DPPC and DPPE. | Sun, R., et al. 2009. Colloids Surf B Biointerfaces. 73: 161-7. PMID: 19576737
- The interactions between cholesterol and phospholipids located in the inner leaflet of human erythrocytes membrane (DPPE and DPPS) in binary and ternary films--the effect of sodium and calcium ions. | Wydro, P. 2011. Colloids Surf B Biointerfaces. 82: 209-16. PMID: 20864321
- Construction of amphiphilic copolymer nanoparticles based on hyperbranched poly (amine-ester) and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine as drug carriers for cancer therapy. | Wu, Y., et al. 2011. Nanomedicine. 7: 945-54. PMID: 21664985
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- A Simple and Efficient Method for Synthesis of sn-Glycero-Phosphoethanolamine. | B Gowda, SG., et al. 2020. Lipids. 55: 395-401. PMID: 32406068
- Molecular chirality mediated amyloid formation on phospholipid surfaces. | Wang, X., et al. 2020. Chem Sci. 11: 7369-7378. PMID: 34123018
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- Influence of cytochrome P450 3A4 and membrane lipid composition on doxorubicin activity. | Dos Santos, KF., et al. 2022. Colloids Surf B Biointerfaces. 220: 112886. PMID: 36183636
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, 50 mg | sc-202870 | 50 mg | $67.00 | |||
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, 250 mg | sc-202870A | 250 mg | $171.00 | |||
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, 5 g | sc-202870B | 5 g | $733.00 | |||
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine, 25 g | sc-202870C | 25 g | $3487.00 |