1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine (CAS 5681-36-7)

1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine is a phosphoethanolamine. 1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine, known as DPPE, is a prevalent phospholipid within the cellular membranes of eukaryotic organisms. Comprising a glycerol backbone, two fatty acid chains, and a phosphate group, this glycerophospholipid displays an amphipathic character—featuring both hydrophobic and hydrophilic domains. Its distinct attributes and versatile applications render 1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine a staple in scientific investigations. The applications of 1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine in scientific research are extensive. It serves as a prime model membrane constituent, forming stable bilayers that simulate natural cell membranes. In studies focused on membrane protein structure and function, it becomes a pivotal element by integrating into liposomes, faithfully mimicking the lipid-rich surroundings of cellular membranes. Beyond this, its role expands to encompass drug delivery systems and the advancement of cutting-edge biosensors. Engaged in a spectrum of biological processes, 1,2-Dipalmitoyl-rac-glycero-3-phosphoethanolamine plays a role in membrane fusion and the formation of lipid rafts. Notably, its interaction with membrane proteins holds the capacity to influence and regulate their activity. Moreover, the impact extends to the physical attributes of cell membranes, impacting fluidity and permeability alike.