1,2-Dioleoyl PC (CAS 4235-95-4)

1,2-Dioleoyl-sn-glycero-3-phosphocholine, commonly abbreviated as 1,2-Dioleoyl PC, with CAS number 4235-95-4, is a phospholipid predominantly utilized in the study of membrane biophysics and the assembly of lipid bilayers. This molecule consists of two oleic acid chains esterified to the first and second carbons of glycerol, with a phosphocholine group attached to the third carbon. This structural configuration grants 1,2-Dioleoyl PC amphipathic properties, making it a critical component in the formation of liposomes and model cell membranes. Researchers leverage these properties to construct artificial lipid bilayers, which are instrumental in studying membrane dynamics, permeability, and interactions with various proteins and other molecules. The fluidic nature of the oleic acid chains in 1,2-Dioleoyl PC contributes to the fluidity of the membranes it forms, closely mimicking the dynamic nature of biological membranes. This has enabled scientists to delve into fundamental questions about lipid-lipid and lipid-protein interactions, which are essential for understanding the underlying mechanisms of membrane function. Additionally, 1,2-Dioleoyl PC is employed in the preparation of nanoscale lipid-based delivery systems for various molecules in research settings, aiding in the investigation of molecule transport and delivery mechanisms across lipid membranes.