1,2-Dimyristoyl-sn-glycero-3-phospho-sn-glycerol sodium salt (CAS 116870-30-5)

1,2-Dimyristoyl-sn-glycero-3-phospho-sn-glycerol sodium salt is a synthetic phospholipid that plays a significant role in membrane biophysics research, particularly in studies related to membrane structure and function. Comprising two myristoyl chains attached to the sn-1 and sn-2 positions of glycerol, with a phosphoglycerol group at the sn-3 position, this molecule is ideal for investigating the effects of lipid composition on membrane dynamics. The inclusion of a glycerol group in the headgroup region affects the hydration and overall stability of lipid bilayers, making it a valuable tool for examining membrane permeability, fluidity, and the interactions between lipids and membrane proteins. The sodium salt enhances its solubility, facilitating its use in aqueous solutions, which is crucial for creating model membranes and liposomes in vitro. Research with this lipid has provided insights into the mechanisms of vesicle fusion, lipid raft formation, and the role of specific phospholipids in signaling pathways. These studies are critical for understanding the fundamental aspects of cellular membranes, contributing to a broader comprehension of cellular functions and interactions.