Date published: 2026-5-8

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1,2-Didecanoyl-sn-glycerol (CAS 60514-49-0)

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Application:
1,2-Didecanoyl-sn-glycerol is an analog of the PKC-activating second messenger DAG
CAS Number:
60514-49-0
Molecular Weight:
400.59
Molecular Formula:
C23H44O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Didecanoyl-sn-glycerol is an analog of the PKC-activating second messenger DAG.


1,2-Didecanoyl-sn-glycerol (CAS 60514-49-0) References

  1. Inhibition of human gastric and pancreatic lipases by chiral alkylphosphonates. A kinetic study with 1,2-didecanoyl-sn-glycerol monolayer.  |  Cavalier, JF., et al. 1999. Chem Phys Lipids. 100: 3-31. PMID: 10640192
  2. Diacylglycerol inhibits potassium-induced calcium influx and insulin release by a protein kinase-C-independent mechanism in HIT T-15 islet cells.  |  Thomas, TP. and Pek, SB. 1992. Endocrinology. 131: 1985-92. PMID: 1396342
  3. Inactivation of pancreatic and gastric lipases by tetrahydrolipstatin and alkyl-dithio-5-(2-nitrobenzoic acid). A kinetic study with 1,2-didecanoyl-sn-glycerol monolayers.  |  Ransac, S., et al. 1991. Eur J Biochem. 202: 395-400. PMID: 1761041
  4. Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.  |  Hirst, JJ., et al. 1990. J Endocrinol. 124: 225-32. PMID: 2155985
  5. A membrane-bound diacylglycerol kinase that selectively phosphorylates arachidonoyl-diacylglycerol. Distinction from cytosolic diacylglycerol kinase and comparison with the membrane-bound enzyme from Escherichia coli.  |  MacDonald, ML., et al. 1988. J Biol Chem. 263: 1584-92. PMID: 2826486
  6. Differential stimulation of the respiratory burst and lysosomal enzyme secretion in human polymorphonuclear leukocytes by synthetic diacylglycerols.  |  Cox, CC., et al. 1986. J Immunol. 136: 4611-6. PMID: 3011896
  7. Mode of activation and kinetic properties of three distinct forms of protein kinase C from rat brain.  |  Sekiguchi, K., et al. 1988. J Biochem. 103: 759-65. PMID: 3182745
  8. Interfacial binding of human gastric lipase to lipid monolayers, measured with an ELISA.  |  Aoubala, M., et al. 1995. Biochemistry. 34: 10786-93. PMID: 7545008
  9. Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector.  |  Zoukhri, D., et al. 1993. Am J Physiol. 264: C1045-50. PMID: 8386449
  10. Differences in mechanisms for cell-free NADPH oxidase activation between arachidonate and sodium dodecyl sulfate.  |  Okamura, N., et al. 1996. Biol Pharm Bull. 19: 1130-5. PMID: 8889029

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Didecanoyl-sn-glycerol, 25 mg

sc-202001
25 mg
$100.00

1,2-Didecanoyl-sn-glycerol, 50 mg

sc-202001A
50 mg
$180.00