1,2-Dichlorohexafluorocyclobutane (CAS 356-18-3)
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1,2-Dichlorohexafluorocyclobutane is a halogenated organic compound that is primarily used in research applications within the fields of materials science and chemistry. Its unique structure, featuring a cyclobutane ring with both chlorine and fluorine atoms, makes it a subject of interest for studying reaction mechanisms and the stability of small ring systems. In materials science, 1,2-Dichlorohexafluorocyclobutane is investigated for its potential applications as a gaseous dielectric medium due to its chemical and thermal stability. Additionally, it is used in the synthesis of more complex fluorinated compounds that have potential applications in advanced materials. In physical chemistry, the compound′s interactions with light and other chemicals are studied to gain insights into the properties of chlorofluorocarbons and their behavior under various conditions. Its role in the development of novel synthetic methodologies also contributes to the broader understanding of organofluorine chemistry.
1,2-Dichlorohexafluorocyclobutane (CAS 356-18-3) References
- Volatile anesthetics increase intracellular calcium in cerebrocortical and hippocampal neurons. | Kindler, CH., et al. 1999. Anesthesiology. 90: 1137-45. PMID: 10201687
- Halothane, but not the nonimmobilizers perfluoropentane and 1,2-dichlorohexafluorocyclobutane, depresses synaptic transmission in hippocampal CA1 neurons in rats. | Taylor, DM., et al. 1999. Anesth Analg. 89: 1040-5. PMID: 10512287
- The nonimmobilizer 1,2-dichlorohexafluorocyclobutane does not affect thermoregulation in the rat. | Maurer, AJ., et al. 2000. Anesth Analg. 91: 1013-6. PMID: 11004066
- The convulsant and anesthetic properties of cis-trans isomers of 1,2-dichlorohexafluorocyclobutane and 1,2-dichloroethylene. | Eger, EI., et al. 2001. Anesth Analg. 93: 922-7. PMID: 11574358
- Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory. | Dutton, RC., et al. 2002. Anesth Analg. 94: 631-9; table of contents. PMID: 11867388
- The differential effect of halothane and 1,2-dichlorohexafluorocyclobutane on in vitro muscle contractures of patients susceptible to malignant hyperthermia. | Kindler, CH., et al. 2002. Anesth Analg. 94: 1028-33, table of contents. PMID: 11916818
- Acetylcholine receptors and thresholds for convulsions from flurothyl and 1,2-dichlorohexafluorocyclobutane. | Eger, EI., et al. 2002. Anesth Analg. 95: 1611-5, table of contents. PMID: 12456426
- Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone. | Eger, EI., et al. 2003. Anesth Analg. 96: 1010-1018. PMID: 12651651
- Effects on synaptic inhibition in the hippocampus do not underlie the amnestic and convulsive properties of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane. | Perouansky, M. and Pearce, RA. 2004. Anesthesiology. 101: 66-74. PMID: 15220773
- The differential effects of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane on extrasynaptic gamma-aminobutyric acid A receptors. | Perouansky, M., et al. 2005. Anesth Analg. 100: 1667-1673. PMID: 15920193
- The gamma-subunit governs the susceptibility of recombinant gamma-aminobutyric acid type A receptors to block by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N). | Zarnowska, ED., et al. 2005. Anesth Analg. 101: 401-406. PMID: 16037152
- Pretreatment with volatile anesthetics, but not with the nonimmobilizer 1,2-dichlorohexafluorocyclobutane, reduced cell injury in rat cerebellar slices after an in vitro simulated ischemia. | Wang, C., et al. 2007. Brain Res. 1152: 201-8. PMID: 17434151
- Amnesic concentrations of the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6, 2N) and isoflurane alter hippocampal theta oscillations in vivo. | Perouansky, M., et al. 2007. Anesthesiology. 106: 1168-76. PMID: 17525592
- Enhancement of α5-containing γ-aminobutyric acid type A receptors by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6) is abolished by the β3(N265M) mutation. | Burkat, PM., et al. 2014. Anesth Analg. 119: 1277-84. PMID: 25211390
- Alteration of lipid bilayer mechanics by volatile anesthetics: Insights from μs-long molecular dynamics simulations. | Zizzi, EA., et al. 2022. iScience. 25: 103946. PMID: 35265816
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2-Dichlorohexafluorocyclobutane, 25 g | sc-265009 | 25 g | $234.00 |