Date published: 2026-5-21

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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (CAS 36314-47-3)

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Alternate Names:
(7R)-7-(Hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt, 1-Hexadecyl-2-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dihexadecyl, L-α-Lecithin dihexadecyl ether, L-α-Phosphatidylcholine, di-O-hexadecyl, L-β,γ-Dihexadecyl-α-lecithin, DCPC, Glycerol-3-sn-phosphorylcholine 1,2-bis(hexadecyl ether), PC(O-16:0/O-16:0)
CAS Number:
36314-47-3
Molecular Weight:
706.07
Molecular Formula:
C40H84NO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine is a lipophilic cationic surfactant extensively utilized in scientific research. This organic compound consists of two hexadecyloxypropyl groups, two trimethylammonioethyl groups, and a phosphate group. It serves as a surfactant, which is a substance capable of lowering the surface tension of a liquid. This property enables the surfactant to interact effectively with the surfaces of particles and other substances, facilitating their manipulation and utilization in various applications within the realm of scientific research.


1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (CAS 36314-47-3) References

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  2. Molecular features of phospholipids that affect glycolipid transfer protein-mediated galactosylceramide transfer between vesicles.  |  Nylund, M., et al. 2006. Biochim Biophys Acta. 1758: 807-12. PMID: 16777057
  3. Thermodynamic invariants of gel to the liquid-crystal 1,2-diacylphosphatidylcholines transition.  |  Potekhin, SA., et al. 2011. Biochim Biophys Acta. 1808: 1806-10. PMID: 21377445
  4. Influence of the interdigitated gel phase in mixtures of ether-linked and monofluorinated ester-linked phospholipids.  |  Smith, EA. and Dea, PK. 2012. Chem Phys Lipids. 165: 818-25. PMID: 23159928
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  6. A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines.  |  Skibinski, CG., et al. 2016. Chem Biol Interact. 252: 1-8. PMID: 27041074
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  9. Influence of a single ether bond on assembly, orientation, and miscibility of phosphocholine lipids at the air-water interface.  |  Hoffmann, M., et al. 2021. Phys Chem Chem Phys. 23: 5325-5339. PMID: 33634294
  10. The effect of cholesterol on lipid dynamics and packing in diether phosphatidylcholine bilayers. X-ray diffraction and 2H-NMR study.  |  Siminovitch, DJ., et al. 1987. Biochim Biophys Acta. 901: 191-200. PMID: 3607045
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  12. Determination of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine products in human very low-density lipoproteins by nonaqueous low-flow capillary electrophoresis-mass spectrometry.  |  Chang, CT., et al. 2023. J Chromatogr A. 1687: 463694. PMID: 36502642
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine, 100 mg

sc-206220
100 mg
$113.00

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine, 500 mg

sc-206220A
500 mg
$337.00