Date published: 2026-3-5

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1,2-Decanediol (CAS 1119-86-4)

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Alternate Names:
1,2-Dihydroxydecane
CAS Number:
1119-86-4
Molecular Weight:
174.28
Molecular Formula:
C10H22O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Decanediol is a compound that functions as a chemical intermediate in research and development. It acts as a building block in the synthesis of various polymers, including polyesters and polyurethanes. This compound participates in condensation reactions, where it reacts with other compounds to form high molecular weight polymers. At the molecular level, 1,2-decanediol undergoes reactions with carboxylic acids and isocyanates to form ester and urethane linkages, respectively. These reactions contribute to the formation of polymeric materials with diverse properties, such as flexibility, durability, and thermal stability. In this context, 1,2-decanediol serves as a key component in the production of polymers with tailored characteristics for specific applications in materials science and engineering. Its mode of action involves participating in chemical reactions that lead to the formation of polymeric materials with desired properties.


1,2-Decanediol (CAS 1119-86-4) References

  1. The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes.  |  Di Caprio, R., et al. 2019. G Ital Dermatol Venereol. 154: 624-631. PMID: 28712268
  2. Pleiotropic Effects of White Willow Bark and 1,2-Decanediol on Human Adult Keratinocytes.  |  Bassino, E., et al. 2018. Skin Pharmacol Physiol. 31: 10-18. PMID: 29131127
  3. Volatilomic insight of head and neck cancer via the effects observed on saliva metabolites.  |  Taware, R., et al. 2018. Sci Rep. 8: 17725. PMID: 30531924
  4. Antibacterial Activity of 1,2-Alkanediol against Staphylococcus aureus and Staphylococcus epidermidis.  |  Okukawa, M., et al. 2019. J Oleo Sci. 68: 759-763. PMID: 31292342
  5. Deoxydehydration of vicinal diols by homogeneous catalysts: a mechanistic overview.  |  DeNike, KA. and Kilyanek, SM. 2019. R Soc Open Sci. 6: 191165. PMID: 31827851
  6. A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population.  |  Kulthanan, K., et al. 2020. Biomed Res Int. 2020: 2857812. PMID: 33150170
  7. Investigation of partially myristoylated carboxymethyl chitosan, an amphoteric-amphiphilic chitosan derivative, as a new material for cosmetic and dermal application.  |  Seino, H., et al. 2021. J Cosmet Dermatol. 20: 2332-2340. PMID: 33174289
  8. Double-headed amphiphile-based sponge droplets: synthesis, characterization and potential for the extraction of compounds over a wide polarity range.  |  González-Rubio, S., et al. 2022. Talanta. 239: 123108. PMID: 34863061
  9. Salivary Metabolomics for Oral Squamous Cell Carcinoma Diagnosis: A Systematic Review.  |  Nijakowski, K., et al. 2022. Metabolites. 12: PMID: 35448481
  10. The Synergy between Pharmacological Regimens and Dermocosmetics and Its Impact on Adherence in Acne Treatment.  |  Araviiskaia, E., et al. 2022. Dermatol Res Pract. 2022: 3644720. PMID: 35982914
  11. Influence of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid on facial skin lipidome among seborrhea participants.  |  Wongtada, C., et al. 2022. J Cosmet Dermatol. 21: 7081-7089. PMID: 36102580
  12. Accuracy improvement of determination of seven minor tobacco alkaloids in mainstream cigarette smoke using analyte protectants by gas chromatography-mass spectrometry.  |  Guo, Q., et al. 2022. J Chromatogr A. 1684: 463537. PMID: 36240707
  13. Salivary Metabolomics for Systemic Cancer Diagnosis: A Systematic Review.  |  Nijakowski, K., et al. 2022. Metabolites. 13: PMID: 36676953

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Decanediol, 25 g

sc-485146
25 g
$60.00