Date published: 2026-4-27

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1,2-Bis(diphenylphosphino)benzene (CAS 13991-08-7)

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CAS Number:
13991-08-7
Purity:
≥97%
Molecular Weight:
446.46
Molecular Formula:
C30H24P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2-Bis(diphenylphosphino)benzene, also known as 1,2-dppb, is an organophosphorus compound widely utilized as a ligand in coordination chemistry. As a bidentate ligand, it has the capability to coordinate with a metal center through two donor atoms. This compound finds extensive applications in organic synthesis, catalysis, and materials science. Within scientific research, 1,2-Bis(diphenylphosphino)benzene has played a significant role. It is frequently employed as a ligand in the synthesis of organometallic compounds, particularly catalysts for organic reactions. Furthermore, it has found utility as a ligand in the creation of coordination polymers, materials that hold potential for energy storage and conversion. Additionally, 1,2-Bis(diphenylphosphino)benzene has served as a ligand in the synthesis of bioactive molecules, including metalloproteins and metalloenzymes. Operating as a bidentate ligand, 1,2-Bis(diphenylphosphino)benzene coordinates to a metal center through its two phosphorus atoms, which are connected by a benzene ring. This structural arrangement enhances the stability of the resulting complex. By donating electron density to the metal center, the two donor atoms form a robust bond between the metal and the ligand.


1,2-Bis(diphenylphosphino)benzene (CAS 13991-08-7) References

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  2. Zerovalent Nickel Compounds Supported by 1,2-Bis(diphenylphosphino)benzene: Synthesis, Structures, and Catalytic Properties.  |  Neary, MC., et al. 2018. Inorg Chem. 57: 374-391. PMID: 29244503
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  4. Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides.  |  Li, C., et al. 2019. Chem Sci. 10: 9285-9291. PMID: 32055314
  5. Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids.  |  Hall, CJJ., et al. 2021. Angew Chem Int Ed Engl. 60: 6981-6985. PMID: 33561302
  6. Anticancer gold(iii)-bisphosphine complex alters the mitochondrial electron transport chain to induce in vivo tumor inhibition.  |  Kim, JH., et al. 2021. Chem Sci. 12: 7467-7479. PMID: 34163837
  7. Fluorinated Cycloplatinated(II) Complexes Bearing Bisphosphine Ligands as Potent Anticancer Agents.  |  Shahsavari, HR., et al. 2021. Organometallics. 40: 72-82. PMID: 34334870
  8. Mononuclear Copper(I) 3-(2-pyridyl)pyrazole Complexes: The Crucial Role of Phosphine on Photoluminescence.  |  Baranova, KF., et al. 2021. Molecules. 26: PMID: 34833961
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  10. Catalytic Enantioselective Synthesis of γ-Lactams with β-Quaternary Centers via Merging of C-C Activation and Sulfonyl Radical Migration.  |  Yu, X., et al. 2022. J Am Chem Soc. 144: 9222-9228. PMID: 35580261
  11. Heterotrimetallic Assemblies with 1,2,4,5-Tetrakis(diphenylphosphino)benzene Bridges: Constructs for Controlling the Separation and Spatial Orientation of Redox-Active Metallodithiolene Groups.  |  Kumar, S., et al. 2022. Inorg Chem. 61: 17804-17818. PMID: 36282620
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2-Bis(diphenylphosphino)benzene, 1 g

sc-222795
1 g
$71.00