Date published: 2025-12-19

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1,2,4-Trichlorobenzene (CAS 120-82-1)

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Alternate Names:
unsym-Trichlorobenzene
Application:
1,2,4-Trichlorobenzene is a compound used in soil and ground water contamination studies.
CAS Number:
120-82-1
Purity:
≥99%
Molecular Weight:
181.45
Molecular Formula:
C6H3Cl3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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1,2,4-Trichlorobenzene, with the CAS number 120-82-1, is an organochlorine compound characterized by the presence of three chlorine atoms attached to a benzene ring. This chemical configuration endows it with unique physical and chemical properties, such as a relatively high density and low solubility in water, but good solubility in organic solvents. In the field of research, 1,2,4-trichlorobenzene has been extensively used as a solvent in organic chemistry due to its ability to dissolve a wide range of organic materials and its stability under various chemical conditions. Its role in research extends to serving as a non-polar, high-boiling solvent in high-temperature chemical reactions, which makes it particularly useful for conducting reactions that require a thermally stable environment. Furthermore, 1,2,4-trichlorobenzene has been utilized in the synthesis of dyes, herbicides, and other organic compounds, demonstrating its versatility in facilitating chemical transformations. Environmental scientists have also studied this compound, focusing on its persistence in the environment and its potential as a bioaccumulative substance. These studies often involve examining its degradation mechanisms, environmental fate, and the impact of its byproducts on ecosystems. Thus, 1,2,4-trichlorobenzene not only serves as a critical tool in chemical synthesis but also as a subject of environmental research, where understanding its long-term effects is crucial for assessing ecological risks.


1,2,4-Trichlorobenzene (CAS 120-82-1) References

  1. Biodegradation of 1,2,3- and 1,2,4-trichlorobenzene in soil and in liquid enrichment culture.  |  Marinucci, AC. and Bartha, R. 1979. Appl Environ Microbiol. 38: 811-7. PMID: 120698
  2. Reductive dechlorination of 1,2,4-trichlorobenzene with palladized nanoscale Fe(zero-valent) particles supported on chitosan and silica.  |  Zhu, BW., et al. 2006. Chemosphere. 65: 1137-45. PMID: 16735054
  3. Isolation and characterization of 1,2,4-trichlorobenzene mineralizing Bordetella sp. and its bioremediation potential in soil.  |  Wang, F., et al. 2007. Chemosphere. 67: 896-902. PMID: 17204305
  4. Sorption of nonpolar neutral organic compounds to model aquifer sands: implications on blocking effect.  |  Joo, JC., et al. 2011. J Environ Sci Health A Tox Hazard Subst Environ Eng. 46: 1008-19. PMID: 21847791
  5. Pathway-dependent isotope fractionation during aerobic and anaerobic degradation of monochlorobenzene and 1,2,4-trichlorobenzene.  |  Liang, X., et al. 2011. Environ Sci Technol. 45: 8321-7. PMID: 21851082
  6. Effects of 1,2,4-trichlorobenzene on the enzyme activities and ultrastructure of earthworm Eisenia fetida.  |  Wu, SJ., et al. 2012. Ecotoxicol Environ Saf. 76: 175-81. PMID: 21962413
  7. Enhanced removal of 1,2,4-trichlorobenzene by modified biochar supported nanoscale zero-valent iron and palladium.  |  Shang, X., et al. 2020. Chemosphere. 249: 126518. PMID: 32213390
  8. Online measurement of 1,2,4-trichlorobenzene as dioxin indicator on multi-walled carbon nanotubes.  |  Mubeen, I., et al. 2021. Environ Pollut. 268: 115329. PMID: 33137681
  9. Exogenous silicon enhances resistance to 1,2,4-trichlorobenzene in rice.  |  Niu, Y., et al. 2022. Sci Total Environ. 845: 157248. PMID: 35820528
  10. Comparative metabolism of 1,2,4-trichlorobenzene in the rat and rhesus monkey.  |  Lingg, RD., et al. 1982. Drug Metab Dispos. 10: 134-41. PMID: 6124398

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2,4-Trichlorobenzene, 1 L

sc-237701
1 L
$116.00
US: Only available in the US